Hyaline Membrane Disease in Newborns

Hyaline Membrane Disease in Newborns

Article
Healthy Lungs
Congenital & Genetic Disorders
Contributed byMaulik P. Purohit MD MPHMar 11, 2018

The topic Hyaline Membrane Disease in Newborns you are seeking is a synonym, or alternative name, or is closely related to the medical condition Infant Respiratory Distress Syndrome.

Quick Summary:

  • Infant Respiratory Distress Syndrome (IRDS) is a breathing disorder in newborns, which results primarily due to premature delivery of the baby. The condition arises owing to reduced amounts of surfactants in immature lungs
  • Surfactants are complex substances that help lower the surface tension of fluids in the lung. This helps keep the alveolar sacs (the sites of oxygen exchange) from collapsing. Thus, a deficiency of surfactants leads to non-compliant and stiff lungs
  • It is estimated that about half of the babies born between weeks 28 and 32 of gestation develop Infant Respiratory Distress Syndrome, which is typically manifested as breathing trouble and bluish discoloration of the skin
  • The diagnosis of Infant Respiratory Distress Syndrome may require chest X-rays and lab tests, apart from physical examination and symptom assessment 
  • Treatment options for a newborn with Infant Respiratory Distress Syndrome are geared toward easing breathing difficulties, which may involve the use of artificial surfactants, oxygen therapy, and the use of a breathing machine (if warranted)
  • If the condition does not get resolved in early infancy, it could develop into a more chronic form known as bronchopulmonary dysplasia. In addition, air or gas build-up might occur around the lungs and between the heart and its outer layer. In serious cases, developmental abnormalities affecting the lungs, eyes, and brain might ensue
  • In case of premature labor, treating the pregnant woman with steroids is reported to aid in lung maturity in the fetus. Taking steps to avoid premature deliveries by good prenatal care is a known preventive method for Infant Respiratory Distress Syndrome
  • If diagnosed and treated promptly, the prognosis of Infant Respiratory Distress Syndrome is considered good. However, the prognosis also depends upon the severity of the condition

Please find comprehensive information on Infant Respiratory Distress Syndrome regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Maulik P. Purohit MD MPH

Assistant Medical Director, Medical Editorial Board, DoveMed Team

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