Hutchinson-Gilford Progeria Syndrome (HGPS)

Hutchinson-Gilford Progeria Syndrome (HGPS)

Article
Congenital & Genetic Disorders
Rare Diseases & Disorders
Contributed byKrish Tangella MD, MBAMar 23, 2018

The topic Hutchinson-Gilford Progeria Syndrome (HGPS) you are seeking is a synonym, or alternative name, or is closely related to the medical condition Progeria.

Quick Summary:

  • Progeria is a rare genetic condition that causes accelerated, premature aging in children. While children appear normal at birth, within the first year of their life, growth rate slows and signs of aging become apparent
  • Mental and emotional development is not impaired in children with Progeria, however physical growth occurs abnormally
  • Towards the end of their life, children with Progeria develop health problems that many elderly adults suffer, including atherosclerosis (hardening of arteries, causing difficulties pumping blood). This leads to life-ending heart attacks, heart failure, and strokes
  • The average life expectancy of a child with Progeria is around 14 years, but some children have died earlier or even lived into their 20s
  • Progeria is a genetic disorder that results from the mutation of Lamin A gene (LMNA) on chromosome 1. However, the condition is not inherited from any of the parents

Please find comprehensive information on Progeria regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

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