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Hemorrhagic Familial Nephritis

Last updated March 5, 2018

Approved by: Krish Tangella MD, MBA, FCAP

Alport Syndrome is typically observed more in males than females. While the disorder is inherited, symptoms do not arise until later in one’s life.


The topic Hemorrhagic Familial Nephritis you are seeking is a synonym, or alternative name, or is closely related to the medical condition Alport Syndrome.

Quick Summary:

  • Alport Syndrome is a genetic disorder that is characterized by damage to the blood vessels in the kidneys, resulting in nephritis (kidney inflammation) and progressive kidney failure
  • As the disorder progresses, kidney disease, hearing loss, and vision-related abnormalities are likely to occur. Complications of Alport Syndrome are end-stage kidney failure, blindness, and vision loss
  • Mutations in the genes coding for collagen production are responsible for the symptoms associated with Alport Syndrome. Collagen is important for forming blood vessels in the kidneys; these vessels (glomeruli) remove water and waste from blood and create urine. When mutations are present, collagen is not produced appropriately and the blood vessels cannot function properly
  • The diagnosis of Alport Syndrome may include a urine test, serum levels of urea and creatinine, and a renal biopsy
  • There is no cure of Alport syndrome; the treatment is aimed at managing the symptoms. The condition cannot also be effectively prevented
  • Males are more commonly affected by Alport Syndrome than females; also, females have a milder condition than males. Women with Alport Syndrome have better prognosis than men

Please find comprehensive information on Alport Syndrome regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Reviewed and Approved by a member of the DoveMed Editorial Board
First uploaded: June 5, 2017
Last updated: March 5, 2018