Ganglion Cell Tumor

Ganglion Cell Tumor

Article
Ear, Nose, & Throat (ENT)
Brain & Nerve
+7
Contributed byKrish Tangella MD, MBADec 15, 2020

The topic Ganglion Cell Tumor you are seeking is a synonym, or alternative name, or is closely related to the medical condition Gangliocytoma Ganglioglioma.

Quick Summary:

  • A Gangliocytoma Ganglioglioma (GG) is a form of brain tumor. A brain tumor may be described as a mass of abnormally growing cells arising from the brain tissue (brain parenchyma and meninges) or the spinal cord (central spine). The brain along-with the spinal cord constitute the central nervous system (CNS) of the body
  • Broadly, brain tumors are classified as benign (non-cancerous) and malignant. Malignant tumors are cancerous and can spread or metastasize to other regions of the body. They generally exhibit rapid growth and, in some cases, may present symptoms during the early stages of development
  • The World Health Organization (WHO) classifies central nervous system tumors according to their grade and histological subtypes. A tumor subtype is determined by a pathologist after examining a tissue biopsy of the tumor under the microscope. This WHO classification system is used by healthcare professionals all over the world in diagnosing and treating these tumors
  • Gangliocytoma Ganglioglioma or Gangliocytoma and Ganglioglioma are well-differentiated neuroepithelial tumors of the brain. When the tumor consist of a proliferation of only ganglion cells, it is termed gangliocytoma. When the tumor consists of both ganglion cells and glial cells, it is called a ganglioglioma
  • Gangliocytoma Ganglioglioma tumors are benign and slow-growing that usually occur in children and young adults. A majority of the tumors are observed in the temporal lobe of the cerebral hemisphere. Per WHO, the tumor is part of a group designated as “neuronal and mixed neuronal glial tumors”
  • The brain is made of two main cell types - the nerve cells (neurons) and glial cells (non-neuronal cells). The nerve cells communicate with each other and relay information (electric signals or nerve impulses) from the peripheral nervous system (PNS) to the CNS. The glial cells support the nerve cells, but do not take part in the transmission of electrical signals
  • Gangliocytoma and Ganglioglioma are WHO grade I brain tumors, meaning they are designated as “low-grade”. Grade I tumors are the most benign of the tumors. They are slow-growing and are not known to infiltrate into the surrounding tissues. They offer a very high chance for surgery to be curative; and thus, have the best prognosis among all brain tumors with long-term survival being noted
  • The cause of formation of Gangliocytoma Ganglioglioma is not well-established. It is reported that a combination of several factors may play a role in their formation, including genetic, environmental, and lifestyle-related. The risk factors include the presence of certain genetic disorders such as Turner syndrome or Cowden syndrome
  • The signs and symptoms of Gangliocytoma Ganglioglioma depends on the location of the tumor and may include seizures, headaches, and increased intracranial pressure. The tumor may be also associated with slurred speech, memory loss, and personality changes; complications may develop during/from the treatment too
  • The treatments for Gangliocytoma Ganglioglioma may primarily involve surgery and radiation therapy. The prognosis depend on a wide variety of factors, including the size of the tumor and overall health status of the individual. In a majority, the overall prognosis is excellent with complete surgical removal of the tumor, since it is a grade I tumor

Please find comprehensive information on Gangliocytoma Ganglioglioma regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Krish Tangella MD, MBA picture
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Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

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