Gadolinium-Associated Nephrogenic Systemic Fibrosis

Gadolinium-Associated Nephrogenic Systemic Fibrosis

Contributed byMaulik P. Purohit MD MPHApr 01, 2018

The topic Gadolinium-Associated Nephrogenic Systemic Fibrosis you are seeking is a synonym, or alternative name, or is closely related to the medical condition Nephrogenic Systemic Fibrosis.

Quick Summary:

  • Nephrogenic Systemic Fibrosis (NSF) is a rare condition observed with the involvement of several internal organs including the skin and eye. In this condition, there can be fibrosis of major organs of the body such as the heart, lungs, or liver, which can result in disruption of their function
  • The cause of the condition is unknown, but it is strongly linked to gadolinium exposure during magnetic resonance angiography (MRA) studies. Also, a majority of cases are known to develop in individuals undergoing dialysis for kidney failure
  • Nephrogenic Systemic Fibrosis mostly affects young, middle-aged, and old adults. The symptoms are systemic and may also include skin thickening, limited range of motion due to joint pain, and weak muscles
  • It is difficult to treat Nephrogenic Systemic Fibrosis; though in some patients, the use of monoclonal antibodies has been found to be beneficial
  • The prognosis of this chronic disorder is typically poor in spite of appropriate treatment, since it is associated with systemic fibrosis and many vital organs are typically affected

Please find comprehensive information on Nephrogenic Systemic Fibrosis regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Maulik P. Purohit MD MPH

Assistant Medical Director, Medical Editorial Board, DoveMed Team

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