First Cranial Nerve Schwannoma

First Cranial Nerve Schwannoma

Article
Ear, Nose, & Throat (ENT)
Brain & Nerve
+3
Contributed byKrish Tangella MD, MBAOct 26, 2020

The topic First Cranial Nerve Schwannoma you are seeking is a synonym, or alternative name, or is closely related to the medical condition Olfactory Nerve Schwannoma.

Quick Summary:

  • Schwannomas are mostly benign tumors that arise from the Schwann cells around the nerves; these tumors are nerve sheath tumors. Schwannomas involving the central nervous system (CNS) are classified as grade I tumors of the cranial and paraspinal nerves, according to the World Health Organization (WHO)
  • WHO grade I brain tumors are the most benign of the brain tumors that are slow-growing and are not known to infiltrate into surrounding tissues. They offer a very high chance for surgery to be curative, and thus, have the best prognosis amongst all brain tumors; long-term survivals are usually noted
  • A majority of schwannomas involve the cranial nerves, particularly cranial nerve VIII (causing vestibular schwannomas). Cranial nerves are 12 pairs of sensory and/or motor nerves having specific functions that connect parts of the head and neck region to the brain. Ten of these pairs originate from the brainstem; two pairs originate from the cerebrum
  • Olfactory Nerve Schwannomas are schwannomas that involve the cranial nerve I (CN I), which is the olfactory nerve responsible for smell. However, it is important to note that both the olfactory and optic nerves (i.e., cranial nerves I and II) do not have Schwann cells. Thus, the origin of schwannomas at these locations is still being debated upon by the scientific community
  • Currently, no causative factors have been identified for Olfactory Nerve Schwannoma, although certain genetic, environmental, and occupational factors have been implicated in schwannoma development. Rarely, the risk factors for the tumor may include the presence of neurofibromatosis type 2, a genetic disorder, and a positive family history of schwannoma
  • Olfactory Nerve Schwannomas are also referred to as intraparenchymal schwannomas. These tumors arise from a brain region known as the anterior cranial fossa and are extremely rare. Apart from a loss of smell, individuals with these tumors may experience headaches, convulsions, visual impairment, and memory deficit. In rare cases, schwannomas are known to undergo malignant transformations
  • In some cases, the healthcare provider may undertake a ‘wait and watch’ approach for small-sized and slow-growing tumors. In many cases, a complete excision by surgery can be curative and the prognosis of Olfactory Nerve Schwannoma is typically excellent. Nevertheless, follow-up care with regular screening and check-ups are necessary and recommended

Please find comprehensive information on Olfactory Nerve Schwannoma regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

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