Familial Thrombotic Thrombocytopenic Purpura

Familial Thrombotic Thrombocytopenic Purpura

Article
Diseases & Conditions
Blood Disorders
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Contributed byMaulik P. Purohit MD MPHOct 31, 2020

The topic Familial Thrombotic Thrombocytopenic Purpura you are seeking is a synonym, or alternative name, or is closely related to the medical condition Thrombotic Thrombocytopenic Purpura.

Quick Summary:

  • Thrombotic Thrombocytopenic Purpura (TTP) is an uncommon disorder that occurs when clots form in the small blood vessels of the body. Numerous small clots formed all over the body can affect various organs such as the heart, kidney, brain, etc.
  • The terminology Thrombotic Thrombocytopenic Purpura can be explained as a collection of 3 terms - blood clots (thrombotic); lower than normal/optimal number of platelets in blood (thrombocytopenic); and purple spots under the skin (purpura)
  • Because TTP is characterized by clots throughout the body, platelets (which are produced from the bone marrow and are responsible for sealing-off surfaces that are detached due to an injury) get spent, which in turn causes a decrease in the platelet count
  • The inherited form of TTP may run in families. The cause for acquired TTP remains unclear; however, certain conditions, such as cancer and treatments for cancer (chemotherapy), are known to predispose an individual to the disorder
  • The most typical symptom of Thrombotic Thrombocytopenic Purpura is bleeding under the skin, which forms red or purple dots. The diagnosis of TTP may be undertaken through physical examinations, medical history analysis, blood tests and other tests, as needed
  • Individuals with Thrombotic Thrombocytopenic Purpura may be treated through blood plasma infusion, when warranted. A prompt treatment of the condition can help make it more manageable

Please find comprehensive information on Thrombotic Thrombocytopenic Purpura regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Maulik P. Purohit MD MPH

Assistant Medical Director, Medical Editorial Board, DoveMed Team

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