The topic Extranodal Marginal Zone Lymphoma of Esophagus you are seeking is a synonym, or alternative name, or is closely related to the medical condition MALT Lymphoma of Esophagus.

Quick Summary:

• Marginal Zone Lymphoma (MZL) is a slow-growing B-cell non-Hodgkin’s lymphoma affecting adults. Marginal Zone Lymphomas are typically not very aggressive and have better prognosis compared to other B-cell lymphomas
• They constitute approximately 10% of all B-cell lymphomas. There are 3 types of MZLs that include:
  • Nodal Marginal Zone Lymphoma
  • Extranodal Marginal Zone Lymphoma
  • Splenic Marginal Zone Lymphoma
• Extranodal Marginal Zone Lymphoma (EMZL) is the most common type of Marginal Zone Lymphoma. It is also known as Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma. Around 1 in 5 MALT lymphoma cases involve the bone marrow
• Generally, Extranodal Marginal Zone Lymphomas do not involve the lymph nodes; they originate/occur outside the lymph nodes. There are 2 types of EMZLs which include:
  • Gastric type, which involves the stomach
  • Non-gastric type, which develops outside the stomach, such as in the small intestine, thyroid gland, salivary gland, lungs, or eyes
• Marginal Zone Lymphoma of Esophagus is a very rare, Non-Gastric Type of Extranodal Marginal Zone Lymphoma. It affects the esophagus (or foodpipe) commonly in older adults. The condition is also known as Esophageal MALT Lymphoma or MALT Lymphoma of Esophagus
• MALT Lymphoma of Esophagus can cause burning sensation in the foodpipe, regurgitation of food, swallowing difficulty, and other general signs and symptoms, such as fatigue, weight loss, and appetite loss
• Chemotherapy, surgery, and other treatment measures may be used for MALT Lymphoma of Esophagus based on the assessment of the physician. A treatment of underlying conditions, such as AIDS, will also be undertaken
• The prognosis depends on many factors including the type of lymphoma, progression of the condition, response to treatment, and overall health of the individual. In general, the prognosis of Esophageal MALT Lymphoma is guarded
• Esophageal lymphomas are known to be associated with HIV infections; they may occur against a background of AIDS. In such cases, they are generally more aggressive and have poorer prognosis

General information on lymphoma and lymphocytes:

• Lymphoma is a type of cancer stemming from uncontrollably dividing lymphocytes (type of white blood cells). There are two types of lymphomas:
  • Hodgkin lymphoma
  • Non-Hodgkin lymphoma
• Lymphocytes are the main white blood cells found in the lymph, which is the fluid of the lymphatic system; just as blood is the fluid of the circulatory system
• Lymphocytes are made in bone marrow, and can develop into either B-cells or T-cells. Gastrointestinal Follicular Lymphoma arises from cancerous B-cells
• Lymph results from filtration of blood as it travels to and from tissues. Lymph is colorless because it lacks red blood cells; instead, it contains lymphocytes. It is central to the immune system
• There are 3 different kinds of lymphocytes:
  • T-lymphocytes or T cells: They help combat infections and abnormalities within the cells (cell-mediated immunity). They fight viruses and cancerous cells
  • B-lymphocytes or B cells: They produce antibodies that are bodily defense proteins, which target foreign invaders outside the cells (humoral immunity). They fight bacterial cells, cell fragments, and other immunogenic elements
  • Natural killer cells or NK cells: They perform diverse functions related to both cell-mediated and humoral immunity. They also scout for cancer cells, a process called immune surveillance

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