The topic Endogenous Ochronosis, you are seeking is a synonym, or alternative name, or is closely related to the medical condition Ochronosis.

Quick Summary:

• Ochronosis is a rare skin condition marked by blue or black discoloration. Individuals, who use skin-lightening agents containing hydroquinone (excessively) are at the highest risk for developing the condition
• Ochronosis may be exogenous or endogenous, meaning that it can develop from external or internal factors
  • Exogenous Ochronosis: It is most commonly caused by the prolonged usage of topical skin agents that contain hydroquinone. Hydroquinone is used to lighten dark patches of skin
  • Endogenous Ochronosis: It commonly develops in association with alkaptonuria, a rare genetic disorder characterized by urine that becomes black, when left standing over time
• The most common symptom of Ochronosis is dark blue-black or grey-blue patches of skin in the affected area. Although, the condition most commonly affects the skin, the cartilage of the ears and sclera (white structure) of eyes can also get affected
• Ochronosis is mainly diagnosed by examination of skin biopsies and a dermoscopy, which is an examination of the skin using a skin surface microscope
• Complications of Ochronosis, especially in endogenous cases, can include prolonged blue-black color of the skin and sore joints, due to a buildup of pigment that get deposited in bones and cartilage
• Treatment methods for this skin condition include preventive measures, stopping the usage of skin-lightening agents containing hydroquinone, sunscreen application, and treatment for alkaptonuria in endogenous cases
• The prognosis of Ochronosis is generally good and the symptoms are known to subside with proper treatment. However, if it is associated with alkaptonuria, Ochronosis is likely to develop into a lifelong condition with no cure

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