The topic Columnar Alteration with Atypia of Breast you are seeking is a synonym, or alternative name, or is closely related to the medical condition Columnar Cell Lesions of Breast with Flat Epithelial Atypia.

Quick Summary:

• Columnar Cell Lesions of Breast with Flat Epithelial Atypia is a recently introduced terminology in the WHO classification of breast tumors. A diagnosis of the condition is made when breast lesions do not have the classical features of atypical ductal hyperplasia or low-grade ductal carcinoma in situ of breast
• The condition is considered to be an atypical ductal proliferative lesion which shows an increased risk for breast cancers (in future). An “uncertain malignant potential” is associated with Columnar Cell Lesions of Breast with Flat Epithelial Atypia, and it may be a precursor lesion to breast cancer
• There are no specific predisposing factors known for Columnar Cell Lesions of Breast with Flat Epithelial Atypia. The cause of this abnormality may be due to genetic factors
• There are no significant signs and symptoms of Columnar Cell Lesions of Breast with Flat Epithelial Atypia noted. However, there is a slight increase in overall risk for breast cancer; and occasionally, some may present with ductal carcinoma in situ (DCIS) or tubular carcinoma of breast
• Columnar Cell Lesions of Breast with Flat Epithelial Atypia is diagnosed on a breast biopsy by a pathologist when examined under the microscope
• If this condition is greater than 1 cm in size than complete excision of the lesion is usually recommended. However, such a recommendation is presently a topic of debate among the medical experts. The prognosis on its surgical removal is generally excellent

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