Anaphylactoid Purpura

Anaphylactoid Purpura

Article
Bone, Muscle, & Joint
Vein & Vascular Health
+10
Contributed byKrish Tangella MD, MBAApr 14, 2020

The topic Anaphylactoid Purpura you are seeking is a synonym, or alternative name, or is closely related to the medical condition IgA Vasculitis.

Quick Summary:

  • IgA Vasculitis (IgAV) is a form of systemic vasculitis that is observed in young children. In this condition, inflammation of the small blood vessels is observed. It can cause damage to various body organs depending on the region affected, due to decreased blood and oxygen supply to the body region
  • IgA Vasculitis was earlier known as Henoch-Schönlein Purpura (HSP). It is characterized by three main manifestations known as the ‘classic triad’ that include red skin rashes (purpura), joint pain (arthritis), and abdominal pain, due to involvement of the skin, muscles and joints, and the gastrointestinal system
  • The exact cause of the condition is not understood, but it is reportedly immune-mediated. Immunoglobulin A (IgA), an antibody in blood that fights body infections, is known to play a significant role in the development of this condition, and hence, it is termed IgA Vasculitis
  • In a majority, IgA Vasculitis develops post bacterial or viral infection of the throat or stomach. A wide range of infections, such as caused by mycoplasma, adenovirus, or herpes simplex virus, are associated with IgA Vasculitis. In some, it is reported that certain medications may trigger the condition
  • In order to establish a diagnosis of IgA Vasculitis, a wide variety of tests and exams may be performed that include blood and urine tests, radiological studies such as CT and MRI scans, including a tissue biopsy, when needed
  • An early diagnosis and appropriate treatment of IgA Vasculitis can lead to a good prognosis. Most individuals recover in 6-8 weeks; the condition is usually self-limiting in most patients without treatment. Children have a much better overall prognosis than adults

Please find comprehensive information on IgA Vasculitis regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

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