Alpha Thalassemia Trait

Alpha Thalassemia Trait

Article
Diseases & Conditions
Congenital & Genetic Disorders
+1
Contributed byKrish Tangella MD, MBAApr 11, 2022

The topic Alpha Thalassemia Trait you are seeking is a synonym, or alternative name, or is closely related to the medical condition Beta Thalassemia Minor.

Quick Summary:

  • Beta Thalassemia Minor (or Thalassemia Minor), a rare genetic blood disorder, is a defect in the synthesis of beta chains of hemoglobin (a protein that carries oxygen to the tissues). Unlike Thalassemia Major, Thalassemia Minor has only one defective beta globin gene
  • A normal hemoglobin molecule is made up of two identical beta and two identical alpha chains. The defective beta chains are compensated by delta chains resulting in formation of hemoglobin A2. Since there is a defect in only one gene of beta globin chain, the normal hemoglobin A production is only minimally reduced. Thus, patients with Thalassemia Minor do not exhibit serious disease condition
  • If both parents of a child are carriers of Thalassemia Minor, then there is a 25% chance that the child develops Thalassemia Major. If only any one parent is affected by Thalassemia Minor, then the disorder will be passed on to the child
  • Most patients affected by Thalassemia Minor have mild anemia, which may be confused for iron deficiency anemia and treated inappropriately for iron deficiency
  • Individuals with Thalassemia Minor do not have any serious medical problems; most of them may not be even aware that they have the disease

Please find comprehensive information on Beta Thalassemia Minor regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

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