Vitamin D source: The body receives vitamin D through the food (or supplements) one takes, which is termed as exogenous. It is also produced on the skin when exposed to sunlight, called endogenous process.
Since, this leads to two types of vitamin D with differing chemical structures, they are named vitamin D2 and vitamin D3. Both vitamin forms have equal significance, though vitamin D3 is formed in the skin and vitamin D2 is found in foods and vitamin preparations.
Individuals in the following scenario may be prescribed vitamin D testing and/or those requiring calcium, phosphorous, magnesium, or vitamin D supplementation. Those with:
Sample required: Blood
Process: Insertion of needle into a vein (arm).
Preparation required: None
There is a general disagreement, all over the world, on what constitute a lower limit of normal vitamin D range, to definitively diagnose a deficiency of vitamin D. However, as explained previously, vitamin D status is usually indicated by the total 25-hydroxyvitamin D (D2 & D3) content in blood.
Low level of 25-hydroxyvitamin D is seen in:
Low level of 1,25-hydroxyvitamin D is seen in:
High level of 25-hydroxyvitamin D is seen in:
High level of 1,25dihydroxy-vitamin D is seen in:
Too much of vitamin D and calcium could damage the kidney, blood vessels, or other organs, due to the process of calcification.
Too less of magnesium may cause reduced calcium levels in the body, leading to problems in parathyroid hormone regulation.
The laboratory test results are NOT to be interpreted as results of a "stand-alone" test. The test results have to be interpreted after correlating with suitable clinical findings and additional supplemental tests/information. Your healthcare providers will explain the meaning of your tests results, based on the overall clinical scenario.
Certain medications that you may be currently taking may influence the outcome of the test. Hence, it is important to inform your healthcare provider, the complete list of medications (including any herbal supplements) you are currently taking. This will help the healthcare provider interpret your test results more accurately and avoid unnecessary chances of a misdiagnosis.
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