Adverse Cutaneous Reactions to Drugs

Adverse Cutaneous Reactions to Drugs

Article
Allergy
Skin Care
+2
Contributed byLester Fahrner, MD+1 moreAug 24, 2021

The topic Adverse Cutaneous Reactions to Drugs you are seeking is a synonym, or alternative name, or is closely related to the medical condition Drug-Induced Eruption of Skin.

Quick Summary:

  • Drug-Induced Eruption of Skin is condition that develops as an adverse reaction to a medication. It is not contagious and it cannot be transmitted from one individual to another
  • The cause of Drug-Induced Eruption of Skin in most cases is an allergy to medication, or a drug intolerance. The onset of the condition can occur at any age
  • It can affect both men and women; although, women are more likely to be diagnosed with Drug-Induced Skin Eruption, as they are at a higher risk for developing an allergic reaction
  • The condition usually results in red bumps appearing all over the skin, swelling of the tongue, and swelling under the larynx (angioedema). It may also result in enlarged lymph nodes (or lymphadenopathy), which may be a serious condition
  • Drug-Induced Eruption of Skin is usually diagnosed by a thorough clinical history and physical examination, as well a blood test and skin prick testing. Treatment measures include immediately discontinuing the use of medication causing the skin eruptions, and the use of steroids and antihistamines
  • Stopping the usage of the offending medication usually results in the disappearance of the skin lesions. Hence, the prognosis of Drug-Induced Eruption of Skin is generally excellent with no known major complications being noted

A special subset of these eruptions is DRESS syndrome or Drug Reaction with Eosinophilia and Systemic Symptoms syndrome. It is a drug-induced hypersensitivity syndrome (DIHS) with rash, fever, swollen lymph nodes, high eosinophil count, low platelets, and increased atypical lymphocytes. The internal organs are also involved. This syndrome is a potentially fatal condition.

Please find comprehensive information on Drug-Induced Eruption of Skin regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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On the Article

Krish Tangella MD, MBA picture
Approved by

Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team
Lester Fahrner, MD picture
Reviewed by

Lester Fahrner, MD

Chief Medical Officer, DoveMed Team

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