A waxy compound, cholesterol is a fat-like substance that occurs throughout the body. Cholesterol is needed in small amounts by the body for maintenance of cell structure and elasticity, as well as synthesis of bile, Vitamin D, and steroid hormones like estrogens and androgens. A small fraction of cholesterol is formed naturally as a part of the body’s physiology, and the remaining is ingested through food. When a person has too much cholesterol, it interacts with various blood constituents and forms a sticky substance. This substance called plaque can stick to the walls of the blood vessels, narrowing them and leading to various ailments.
Cholesterol is a component of various lipoproteins, namely: Very Low Density Lipoproteins (VLDL), Low Density Lipoproteins (LDL), and High Density Lipoproteins (HDL). The more lipids (naturally occurring substance containing fat, sterols, etc.) a lipoprotein contains, the lighter in density it becomes. This is the reason for lipid testing in blood, and doctors generally prefer to see more HDL (good cholesterol) than LDL (bad cholesterol) in test results.
The bad cholesterol causes clogging and deposition of fat in the arteries that increase blood pressure and the risk of strokes and atherosclerosis. Apart from this, the adipose, fat around organs, glycogen storages, and blood sugar levels are raised. The HDL, according to Durstine and colleagues in a 1994 study, reverses this mechanism by transporting excess fat into the liver so that it can be metabolized and burnt instead of accumulating in the body. This is why HDL is termed as the “good cholesterol.” The American Heart Association states that an increase in levels of bad cholesterol pose a risk of cardiovascular diseases and can be fatal.
Elevating HDL Cholesterol:
Heart disease is the leading cause of death in the USA, as well as globally. Regular lipid profile tests, maintenance of a healthy lifestyle, and food routines are key to sustaining a healthy heart, along with following a medication regimen, if needed.
References:
Brumit, M.L. (2013 Nov 28). How to Lower Your Elevated LDL Cholesterol. Retrieved from http://thefhfoundation.org/lower-elevated-ldl-cholesterol/
(2012 Nov 9). HDL cholesterol: How to boost your ‘good’ cholesterol. Retrieved from http://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/hdl-cholesterol/art-20046388?pg=2
(2014 Jul 31). Prevention and Treatment of High Cholesterol. Retrieved from http://www.heart.org/HEARTORG/Conditions/Cholesterol/PreventionTreatmentofHighCholesterol/Prevention-and-Treatment-of-High-Cholesterol_UCM_001215_Article.jsp
Lower Your Cholesterol with Plant Sterols and Stanols. Retrieved from http://www.joslin.org/info/lower-cholesterol-with-plant-sterols-and-stanols.html
10 High Cholesterol Foods to Avoid: A List of Foods High in Cholesterol. Retrieved from http://www.cholesterol-loweringfoods.org/high-cholesterol-foods/
Vella, C.A., Kravitz, L. & Janot, J.M. A Review of the Impact of Exercise on Cholesterol Levels. Retrieved from http://www.unm.edu/~lkravitz/Article%20folder/cholesterolNEW.html
De Oliveira e Silva, E.R., Foster, D., McGee Harper, M., Seidman, C.E., Smith, J.D. Brewslow, J.L., & Brinton, E.A. (2000). Alcohol Consumption Raises HDL Cholesterol Levels by Increasing the Transport Rate of Apolipoproteins A-I and A-II. Circulation, 102, pp. 2347-2352. Retrieved from http://circ.ahajournals.org/content/102/19/2347.full
(2015 Jan 20). Leading Causes of Death. Retrieved from http://www.cdc.gov/nchs/fastats/leading-causes-of-death.htm
(2014 May). The top 10 causes of death. Retrieved from http://www.who.int/mediacentre/factsheets/fs310/en/
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