In a study published online by JAMA Surgery, Annemarie G. Hirsch, Ph.D., M.P.H., of the Geisinger Health System, Danville, Pa., and colleagues examined whether the DiaRem score, a validated score generated from data readily available could be used to predict patients for whom bariatric surgery will result in cure of type 2 diabetes. This score can be used to predict whether bariatric surgery will lead to short-term remission of diabetes.
The DiaRem score ranges from 0-22 points and is based on age, insulin dependence, diabetes medication use, and hemoglobin A1c level. The researchers reviewed electronic health records up to 8 years after Roux-en-y gastric bypass (RYGB) surgery for 407 patients with type 2 diabetes. The sample was a subset of patients from the original validation study of DiaRem who had at least 5 years of electronic health record data postoperatively. Complete remission was defined as return to normal glycemic measures and no treatment for 1 year. Patients were classified as cured if complete remission lasted at least 5 years.
Of the 407 patients, 35 percent experienced 1 or more years of complete remission and another 24 percent had partial remission lasting at least 1 year. Cure of diabetes was found in 20 percent of patients, and another 25 percent had prolonged partial remission. For remissions of any duration, the proportion of patients achieving remission decreased as DiaRem scores increased. Among the 100 patients with a score from 0 to 2, 82 percent experienced prolonged partial remission compared with none of the 33 patients with a score of 18 or higher. Fifty of the 100 patients with a score of 0 to 2 were cured of diabetes compared with none of the 33 patients with a score of 18 or higher.
"We now show that the DiaRem score predicts who will be cured by surgery, defined as complete remission lasting at least 5 years. The recent efforts to build larger cohorts, gather more data, and develop new analytical capabilities do not preclude continued exploration into how existing data assets can be used to improve the precision of care today," the authors write.
The above post is reprinted from materials provided by The JAMA Network Journals. Note: Materials may be edited for content and length.
Disclaimer: DoveMed is not responsible for the adapted accuracy of news releases posted to DoveMed by contributing universities and institutions.
Primary Resource:
Wood, G. C., Mirshahi, T., Still, C. D., & Hirsch, A. G. (2016). Association of DiaRem Score With Cure of Type 2 Diabetes Following Bariatric Surgery.JAMA surgery.
and connect with fellow professionals
At DoveMed, our utmost priority is your well-being. We are an online medical resource dedicated to providing you with accurate and up-to-date information on a wide range of medical topics. But we're more than just an information hub - we genuinely care about your health journey. That's why we offer a variety of products tailored for both healthcare consumers and professionals, because we believe in empowering everyone involved in the care process.
Our mission is to create a user-friendly healthcare technology portal that helps you make better decisions about your overall health and well-being. We understand that navigating the complexities of healthcare can be overwhelming, so we strive to be a reliable and compassionate companion on your path to wellness.
As an impartial and trusted online resource, we connect healthcare seekers, physicians, and hospitals in a marketplace that promotes a higher quality, easy-to-use healthcare experience. You can trust that our content is unbiased and impartial, as it is trusted by physicians, researchers, and university professors around the globe. Importantly, we are not influenced or owned by any pharmaceutical, medical, or media companies. At DoveMed, we are a group of passionate individuals who deeply care about improving health and wellness for people everywhere. Your well-being is at the heart of everything we do.
0 Comments
Please log in to post a comment.