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Adiponectin Blood Test

Last updated Sept. 12, 2018

The Adiponectin Blood Test determines the levels of adiponectin in blood. It is used to diagnose metabolic disorders such as type II diabetes.


What are other Names for this Test? (Equivalent Terms)

  • Adiponectin Blood Levels Test
  • AdipoQ Blood Test
  • CBP-28 Blood Test

What is the Adiponectin Blood Test? (Background Information)

  • Adiponectin is a hormone released by fat cells. It helps regulate tissue inflammation and responsiveness to insulin
  • Insulin is made by beta cells of the pancreas. It is released in blood after a rise in blood glucose level (such as after a heavy meal) to help lower it to normal levels. Insulin does this by stimulating cells to ‘take in’ glucose (and other nutrients)
  • The most common cause of elevated glucose is diabetes mellitus, or just “diabetes”. There are 3 types of diabetes mellitus, all of which affect insulin function:
    • Type 1 or insulin-dependent diabetes results from the autoimmune destruction of beta cells of the pancreas
    • Type 2 or insulin-independent diabetes results from the desensitization of cells to the effects of insulin
    • Gestational diabetes may occur during pregnancy and result in excessively large babies that exhibit low glucose levels
  • Insulin sensitivity refers to the extent to which cells respond to insulin. Diabetes, obesity, and other metabolic disorders are associated with low insulin sensitivity
  • Adiponectin raises insulin sensitivity. It increases the breakdown of fatty acids and decreases the production of glucose by the liver. Individuals with obesity, type II diabetes, and other metabolic disorders often have low adiponectin levels in blood
  • The Adiponectin Blood Test determines the levels of adiponectin in blood. It is used to diagnose metabolic disorders such as type II diabetes

What are the Clinical Indications for performing the Adiponectin Blood Test?

Following are the clinical indications for performing the Adiponectin Blood Test:

  • Frequent urination
  • Increased thirst
  • Fatigue
  • Blurry vision
  • Rapid weight loss
  • Tingling and numbing in the extremities
  • Obesity
  • History of cardiovascular disease

How is the Specimen Collected for the Adiponectin Blood Test?

Following is the specimen collection process for Adiponectin Blood Test:

Sample required: Blood

Process of obtaining blood sample in adults:

  • A band is wrapped around the arm, 3-4 inches above the collection site (superficial vein that lies within the elbow pit)
  • The site is cleaned with 70% alcohol in an outward spiral, away from the zone of needle insertion
  • The needle cap is removed and is held in line with the vein, pulling the skin tight
  • With a small and quick thrust, the vein is penetrated using the needle
  • The required amount of blood sample is collected by pulling the plunger of the syringe out slowly
  • The wrap band is removed, gauze is placed on the collection site, and the needle is removed
  • The blood is immediately transferred into the blood container, which has the appropriate preservative/clot activator/anti-coagulant
  • The syringe and the needle are disposed into the appropriate “sharp container” for safe and hygienic disposal

Preparation required: No special preparation is needed prior to the test.

What is the Significance of the Adiponectin Blood Test Result?

A low Adiponectin Blood Test value may indicate:

  • Type 2 diabetes mellitus
  • Metabolic syndrome

The laboratory test results are NOT to be interpreted as results of a "stand-alone" test. The test results have to be interpreted after correlating with suitable clinical findings and additional supplemental tests/information. Your healthcare providers will explain the meaning of your tests results, based on the overall clinical scenario.

Additional and Relevant Useful Information:

  • Certain factors may interfere with the results of the Adiponectin Blood Test. These include stress, pregnancy, and recent diet and exercise
  • Diabetes insipidus is a rare disorder whereby the kidneys cannot conserve water

Certain medications that you may be currently taking may influence the outcome of the test. Hence, it is important to inform your healthcare provider of the complete list of medications (including any herbal supplements) you are currently taking. This will help the healthcare provider interpret your test results more accurately and avoid unnecessary chances of a misdiagnosis.

What are some Useful Resources for Additional Information?


References and Information Sources used for the Article:


Reviewed and Approved by a member of the DoveMed Editorial Board
First uploaded: Oct. 30, 2015
Last updated: Sept. 12, 2018