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Hyperlipidemia Type 3

Last updated June 23, 2020

Approved by: Maulik P. Purohit MD, MPH

Familial Dysbetalipoproteinemia (FD) is a hereditary disorder characterized by high amounts of lipids (fat) in the body and blood. In this disorder, there is defective breakdown or metabolism of lipids.


The topic Hyperlipidemia Type 3 you are seeking is a synonym, or alternative name, or is closely related to the medical condition Familial Dysbetalipoproteinemia.

Quick Summary:

  • Familial Dysbetalipoproteinemia (FD) is a hereditary disorder characterized by high amounts of lipids (fat) in the body and blood. In this disorder, there is defective breakdown or metabolism of lipids
  • In blood, excess lipids (cholesterol and triglycerides) get laid down on the inner layer of the blood vessels (atherosclerosis), leading to narrowing of the blood vessel tube and finally leading to blockage. When an obstruction occurs in the blood vessels of the heart (coronary), it can cause chest pain and heart attacks
  • In the body, the lipids get deposited in the skin, underneath the skin (subcutaneous) and in the tendons. This is seen as multiple, soft yellow lipid-filled lumps on the skin (xanthomas) or tendons
  • Familial Dysbetalipoproteinemia is inherited in an autosomal recessive manner, which means that the individual inherits 2 defective genes (forming a gene pair) from each parent and the disease is manifested
  • Familial Dysbetalipoproteinemia has a favorable outcome, if there is an early diagnosis of the condition, which is followed by FD management measures such as lipid-lowering therapy and dietary and lifestyle modifications
  • Without treatment, the affected individuals have a 5 to 10  times higher risk of heart attacks, stroke, etc. than the general population

Please find comprehensive information on Familial Dysbetalipoproteinemia regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Reviewed and Approved by a member of the DoveMed Editorial Board
First uploaded: July 1, 2017
Last updated: June 23, 2020