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Acute Generalized Peritonitis

Last updated June 13, 2017

Approved by: Maulik P. Purohit MD, MPH

Spontaneous Peritonitis is an infection of the peritoneal (abdominal) cavity. It is usually the end-result of a severe kidney or liver disease.


The topic Acute Generalized Peritonitis you are seeking is a synonym, or alternative name, or is closely related to the medical condition Spontaneous Peritonitis.

Quick Summary:

  • Spontaneous Peritonitis is an infection of the peritoneal (abdominal) cavity. It is usually the end-result of a severe kidney or liver disease
  • The peritoneal cavity is a space between the parietal and visceral peritoneum, between the two membranes that separate the abdominal organs from the abdominal wall
  • Spontaneous Peritonitis is an acute bacterial infection most commonly caused by Escherichia coli and Klebsiella species. Hence, it is also known as Spontaneous Bacterial Peritonitis (SBP)
  • The condition may also be called ascitic fluid infection. Ascitic fluid (or ascites) is a fluid that abnormally accumulates in the peritoneal cavity, commonly in patients with end-stage liver damage
  • Common signs and symptoms of Spontaneous Peritonitis are abdominal pain and tenderness, fever, chills, nausea, vomiting, and altered mental status
  • Spontaneous Peritonitis is typically treated with intravenous antibiotics. However, the prognosis of the condition is not good. Even on intensive treatment, the death rate is between 10-30%

Please find comprehensive information on Spontaneous Peritonitis regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

What are some Useful Resources for Additional Information?

Centers for Disease Control and Prevention (CDC)
1600 Clifton Rd. Atlanta, GA 30333, USA
Phone: (404) 639-3534
Toll-Free: 800-CDC-INFO (800-232-4636)
TTY: (888) 232-6348
Email: cdcinfo@cdc.gov
Website: http://www.cdc.gov

References and Information Sources used for the Article:

http://www.nlm.nih.gov/medlineplus/ency/article/000648.htm (accessed on 6/14/2017)

http://www.umm.edu/ency/article/000648.htm (accessed on 6/14/2017)

http://portal.mah.harvard.edu/templatesnew/departments/BID/medicinehousestaff/ (accessed on 5/2/2015)

http://www.ccjm.org/content/71/7/569.full.pdf (accessed on 6/14/2017)

http://www.the-hospitalist.org/article/ (accessed on 6/14/2017)

Helpful Peer-Reviewed Medical Articles:

Steinberg, D. (1979). On leaving the peritoneal cavity open in acute generalized suppurative peritonitis. The American Journal of Surgery, 137(2), 216-220.

Nagorney, D. M., Adson, M. A., & Pemberton, J. H. (1985). Sigmoid diverticulitis with perforation and generalized peritonitis. Diseases of the Colon & Rectum, 28(2), 71-75.

Adesunkanmi, A. R. K., Oseni, S. A., Adejuyigbe, O., & Agbakwuru, E. A. (2003). Acute generalized peritonitis in African children: assessment of severity of illness using modified APACHE II score. ANZ journal of surgery, 73(5), 275-279.

Myers, E., Hurley, M., O'sullivan, G. C., Kavanagh, D., Wilson, I., & Winter, D. C. (2008). Laparoscopic peritoneal lavage for generalized peritonitis due to perforated diverticulitis. British Journal of Surgery, 95(1), 97-101.

O'Sullivan, G. C., Murphy, D., O'Brien, M. G., & Ireland, A. (1996). Laparoscopic management of generalized peritonitis due to perforated colonic diverticula. The American journal of surgery, 171(4), 432-434.

Reviewed and Approved by a member of the DoveMed Editorial Board
First uploaded: June 13, 2017
Last updated: June 13, 2017