There are two types of Prostate Specific Antigen; free Prostate Specific Antigen and Complex Prostate Specific Antigen (PSA-bound to protein). Usually, the PSA Blood Test refers to the total Prostate Specific Antigen (both free and complex PSA).
The Prostate Specific Antigen Test is a good tool to detect prostate cancer, though not a perfect one, because PSA levels are increased with many other conditions, like benign prostate enlargement, old age, prostate infections, and with interventional procedures, like cystoscopy (a procedure used to visualize the bladder).
Prostate Specific Antigen Blood Test is used to screen for prostate cancer in men. There is no data available on the benefit of screening non-symptomatic men. PSA is used to monitor the response to treatment and recurrence in patients with prostate cancer, and to screen men with symptoms of prostate cancer. These include:
There is no specific data regarding how frequently one has to be tested. It is dependent upon the condition of each individual patient, and based on the healthcare provider’s judgment.
Sample required: Blood
Process:Insertion of needle into a vein (arm).
Preparation required:
In addition to the introduction of the free Prostate Specific Antigen and complex Prostate Specific Antigen tests, there have been efforts to increase the usefulness of the total Prostate Specific Antigen, as a screening tool. They include:
In individuals already diagnosed with prostate cancer, PSA values should decrease with treatment.If concentrations do not fall to very low levels, then the treatment has not been fully effective.
Following treatment, the Prostate Specific Antigen Blood Test is performed at regular intervals to monitor for any cancer recurrence. Since, even tiny increases can be significant, those affected may want to have their ‘monitoring’ PSA Tests done by the same laboratory each time, so that testing variation is kept to a minimum.
The laboratory test results are NOT to be interpreted as results of a "stand-alone" test. The test results have to be interpreted after correlating with suitable clinical findings and additional supplemental tests/information. Your healthcare providers will explain the meaning of your tests results, based on the overall clinical scenario.
Certain medications that you may be currently taking may influence the outcome of the test. Hence, it is important to inform your healthcare provider, the complete list of medications (including any herbal supplements) you are currently taking. This will help the healthcare provider interpret your test results more accurately and avoid unnecessary chances of a misdiagnosis.
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