An individual with G6PD deficiency may have episodes of hemolysis (destruction of red blood cells) on exposure to certain drugs, food stuffs, infections, or even stress. This may produce symptoms, such as:
G6PD levels may then be checked to investigate the likely cause of hemolysis, especially in individuals with multiple such episodes and also in the setting of hemolysis, with a likely preceding trigger. G6PD Testing may also be done in children, with a history of persistent jaundice as a newborn.
Sample required: Blood
Process:
Preparation required: Testing for G6PD levels should not be done when an individual is having an active hemolytic episode, as this may give false results. Testing should be performed, only when the crisis has resolved.
A low level of G6PD indicates deficiency and the possibility of hemolysis on exposure to certain triggers. It does not, however, predict the severity of the symptoms.
The laboratory test results are NOT to be interpreted as results of a "stand-alone" test. The test results have to be interpreted after correlating with suitable clinical findings and additional supplemental tests/information. Your healthcare providers will explain the meaning of your tests results, based on the overall clinical scenario.
G6PD Testing should not be done immediately following a blood transfusion, as this may mask any deficiencies.
Certain medications that you may be currently taking may influence the outcome of the test. Hence, it is important to inform your healthcare provider, the complete list of medications (including any herbal supplements) you are currently taking. This will help the healthcare provider interpret your test results more accurately and avoid unnecessary chances of a misdiagnosis.
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