Diffuse Laminar Endocervical Hyperplasia of Uterine Cervix

Diffuse Laminar Endocervical Hyperplasia of Uterine Cervix

Article
Sexual Health
Women's Health
+2
Contributed byKrish Tangella MD, MBAAug 29, 2018

What are the other Names for this Condition? (Also known as/Synonyms)

  • Cervical Diffuse Laminar Endocervical Hyperplasia
  • Diffuse Laminar Endocervical Hyperplasia of Cervix
  • DLEH of Uterine Cervix

What is Diffuse Laminar Endocervical Hyperplasia of Uterine Cervix? (Definition/Background Information)

  • Diffuse Laminar Endocervical Hyperplasia (DLEH) of Uterine Cervix is a benign condition that occurs due to an abnormal increase of glands (endocervical glands) within the cervix
  • It is mostly diagnosed in premenopausal status women. The cause of Diffuse Laminar Endocervical Hyperplasia of Cervix is unknown and the risk factors are unidentified
  • Diffuse laminar endocervical hyperplasia is typically seen as a band near the endocervical canal. It is not associated with any significant signs and symptoms or complications. Thus, a diagnosis of DLEH of Cervix can be challenging
  • Treatment course includes observation of the mass in asymptomatic cases and surgical management, if necessary. In general, the prognosis of Diffuse Laminar Endocervical Hyperplasia of Uterine Cervix is excellent with suitable treatment

Who gets Diffuse Laminar Endocervical Hyperplasia of Uterine Cervix? (Age and Sex Distribution)

  • Diffuse Laminar Endocervical Hyperplasia of Uterine Cervix is typically observed in adult women prior to menopause (approximately age 48 years and younger)
  • There is no known ethnic or racial preference

What are the Risk Factors for Diffuse Laminar Endocervical Hyperplasia of Uterine Cervix? (Predisposing Factors)

  • No definitive risk factors have been identified for Diffuse Laminar Endocervical Hyperplasia of Uterine Cervix

It is important to note that having a risk factor does not mean that one will get the condition. A risk factor increases ones chances of getting a condition compared to an individual without the risk factors. Some risk factors are more important than others.

Also, not having a risk factor does not mean that an individual will not get the condition. It is always important to discuss the effect of risk factors with your healthcare provider.

What are the Causes of Diffuse Laminar Endocervical Hyperplasia of Uterine Cervix? (Etiology)

Currently, the exact cause and mechanism of formation of Diffuse Laminar Endocervical Hyperplasia of Uterine Cervix is unknown.

What are the Signs and Symptoms of Diffuse Laminar Endocervical Hyperplasia of Uterine Cervix?

Generally, no signs and symptoms of Diffuse Laminar Endocervical Hyperplasia of Uterine Cervix are observed and a majority of affected women are asymptomatic. In some cases, the following signs and symptoms may be noted:

  • Abnormal vaginal bleeding
  • DLEH is seen as a distinct band typically near the endocervical canal

How is Diffuse Laminar Endocervical Hyperplasia of Uterine Cervix Diagnosed?

A diagnosis of Diffuse Laminar Endocervical Hyperplasia of Uterine Cervix may involve the following steps:

  • Evaluation of the individual’s medical history and a thorough physical (pelvic) examination
  • Transvaginal ultrasound scan
  • Colposcopy: The cervix is examined with an instrument, called a colposcope. This helps the physician get a magnified view of the cervix

Cervical biopsy: It is the process of removing tissue for examination under a microscope by a pathologist. In the case of DLEH, a complete excision and removal of the mass can help in the process of a biopsy, as well as be a means for treating the condition.

A pathologist looks at the tissue sample under a microscope, to detect any evidence of cancer. Types of cervical biopsies include:

  • Colposcopic biopsy: The abnormal areas of the cervix are visualized with a colposcope. After numbing the cervix with a local anesthetic, an instrument, called a biopsy forceps, is used to get a tissue sample. Mild cramps, pain, and some light bleeding, may occur following the procedure
  • Endocervical curettage (endocervical scraping): The curette is an instrument that can be used to scrape out tissue. Using a curette, cells are scraped out from the endocervix (the inner part of the cervix, close to the uterus/womb) and examined under a microscope. Mild pain and bleeding may be present following the procedure

Note:

  • Diffuse Laminar Endocervical Hyperplasia of Cervix is an incidental finding in most cases, while the individual is being examined for other medical conditions. The diagnosis of the condition can be very challenging
  • This condition can be confused with minimal deviation adenocarcinoma, and hence, a careful examination is necessary

Many clinical conditions may have similar signs and symptoms. Your healthcare provider may perform additional tests to rule out other clinical conditions to arrive at a definitive diagnosis.

What are the possible Complications of Diffuse Laminar Endocervical Hyperplasia of Uterine Cervix?

Significant complications from Diffuse Laminar Endocervical Hyperplasia of Cervix are generally not noted, because it is a benign condition.

How is Diffuse Laminar Endocervical Hyperplasia of Uterine Cervix Treated?

Treatment measures for Diffuse Laminar Endocervical Hyperplasia of Uterine Cervix may include the following:

  • If there are no symptoms, then the healthcare provider may chose not to treat the condition
  • If it forms a mass, then surgical intervention with complete excision is usually considered
  • Post-operative care is important: Minimum activity level is to be ensured until the surgical wound heals
  • Follow-up care with regular screening and check-ups are important

How can Diffuse Laminar Endocervical Hyperplasia of Uterine Cervix be Prevented?

  • Current medical research has not established a method of preventing Diffuse Laminar Endocervical Hyperplasia of Uterine Cervix
  • Medical screening at regular intervals with scans and physical examinations are advised

What is the Prognosis of Diffuse Laminar Endocervical Hyperplasia of Uterine Cervix? (Outcomes/Resolutions)

The prognosis of Diffuse Laminar Endocervical Hyperplasia of Uterine Cervix is excellent with appropriate treatment, since it is a benign condition.

Additional and Relevant Useful Information for Diffuse Laminar Endocervical Hyperplasia of Uterine Cervix:

Please visit our Women’s Health center for more physician-approved health information:

http://www.dovemed.com/healthy-living/womens-health/

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Krish Tangella MD, MBA picture
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Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

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