What are the other Names for this Condition? (Also known as/Synonyms)

• Placental Chorangiosis

What is Chorangiosis of Placenta? (Definition/Background Information)

• Chorangiosis of Placenta is a vascular condition characterized by an increased number of blood vessels in the chorionic villi
• The placenta is an organ that connects the developing fetus to the uterine wall. It is a disc shaped reddish brown structure that connects the fetus to the mother through the umbilical cord
• The umbilical cord contains two umbilical arteries and one umbilical vein, providing a connection between maternal and fetal blood circulation
• The normal function of placenta is to supply nutrients and oxygen to the fetus from the mother’s blood and remove wastes from the fetal body
• The chorion and amnion are placental membranes. The chorion is the membrane that is present between the growing fetus and the mother. The amnion closely covers and protects the developing embryo
• Chorionic villi are small structures that arise from the chorionic membrane, and their function is to increase contact between maternal and fetal blood circulation
• Normal chorionic villi have less than 5 capillaries, but in Chorangiosis of Placenta, at least 10 villi contain more than 10 capillaries (vascular channels)
• The risk factors associated with Chorangiosis of Placenta are pre-eclampsia, diabetes mellitus, high altitudes, certain drugs, and urinary tract infections
• There are no specific signs and symptoms associated with this condition. The diagnosis of Chorangiosis of Placenta is made by microscopic examination of the placenta by the pathologist
• Currently, there is no cure and prevention for Chorangiosis of Placenta. It is associated with an increased risk of fetal and neonatal deaths

Who gets Chorangiosis of Placenta? (Age and Sex Distribution)

• Chorangiosis of Placenta can occur in pregnant women of all ages
• There is no racial, ethnic, or geographical predilection

What are the Risk Factors for Chorangiosis of Placenta? (Predisposing Factors)

Risk factors associated with Chorangiosis of Placenta include:

• Diabetes mellitus
• Pre-eclampsia: A pregnancy complication characterized by high blood pressure and signs of kidney damage in the mother
• High altitudes
• Certain drugs
• Urinary tract infections (UTIs)

It is important to note that having a risk factor does not mean that one will get the condition. A risk factor increases ones chances of getting a condition compared to an individual without the risk factors. Some risk factors are more important than others.
Also, not having a risk factor does not mean that an individual will not get the condition. It is always important to discuss the effect of risk factors with your healthcare provider.

What are the Causes of Chorangiosis of Placenta? (Etiology)

• The exact cause of Chorangiosis of Placenta is unknown
• Studies have shown an association between Chorangiosis of Placenta and long-standing decreased perfusion (delivery of blood) of placental tissue

What are the Signs and Symptoms of Chorangiosis of Placenta?

There are no specific signs and symptoms associated with Chorangiosis of Placenta.

How is Chorangiosis of Placenta Diagnosed?

A diagnosis of Chorangiosis of Placenta is made by the microscopic examination of the placenta.

• Cells and tissues are examined by a pathologist under a microscope. Pathological examination is generally considered to be a ‘gold standard’ for a definitive diagnosis
• The pathologist arrives at a diagnosis after analyzing pathology findings along with clinical information of the patient. A pathologist may perform special studies on tissue samples to aid in the final diagnosis (if required)

Many clinical conditions may have similar signs and symptoms. Your healthcare provider may perform additional tests to rule out other clinical conditions to arrive at a definitive diagnosis.

What are the possible Complications of Chorangiosis of Placenta?

Chorangiosis of Placenta is associated with an increased risk of fetal and neonatal deaths.

How is Chorangiosis of Placenta Treated?

There is no specific treatment for Chorangiosis of Placenta.

How can Chorangiosis of Placenta be Prevented?

Currently, there are no definitive methods available to prevent Chorangiosis of Placenta.

What is the Prognosis of Chorangiosis of Placenta? (Outcomes/Resolutions)

• Chorangiosis of Placenta is very rarely seen in normal pregnancies
• The condition is associated with an increased risk of fetal and neonatal deaths

Additional and Relevant Useful Information for Chorangiosis of Placenta:

The following DoveMed website link is a useful resource for additional information:

https://www.dovemed.com/diseases-conditions/pregnancy-related-disorders/