What are the other Names for this Condition? (Also known as/Synonyms)

• Placental Chorangiomatosis

What is Chorangiomatosis of Placenta? (Definition/Background Information)

• Chorangiomatosis of Placenta is a condition characterized by the proliferation of small blood vessels in the chorionic villi of the placenta
• The placenta is an organ that connects the developing fetus to the uterine wall. It is a disc shaped reddish brown structure that connects the fetus to the mother through the umbilical cord
• The umbilical cord contains two umbilical arteries and one umbilical vein, providing a connection between maternal and fetal blood circulation
• The normal function of placenta is to supply nutrients and oxygen to the fetus from the mother’s blood and remove wastes from the fetal body
• The chorion and amnion are placental membranes. The chorion is the membrane that is present between the growing fetus and the mother. The amnion closely covers and protects the developing embryo
• Chorionic villi are small structures that arise from the chorionic membrane, and their function is to increase contact between maternal and fetal blood circulation
• Chorangiomatosis of Placenta could be focal (involving less than 5 villi) or it could be diffuse (involving several villi). There are no known risk factors associated with the condtion
• The exact cause of Chorangiomatosis of Placenta is currently unknown. There is also no specific treatment and prevention of Chorangiomatosis of Placenta
• Complications associated with Chorangiomatosis of Placenta include pre-eclampsia, premature delivery, congenital malformations, and growth restriction of the fetus. Diffuse chorangiomatosis is associated with worse prognostic outcomes

Who gets Chorangiomatosis of Placenta? (Age and Sex Distribution)

• Chorangiomatosis of Placenta can occur in pregnant women of all ages
• There is no racial, ethnic, or geographical predilection

What are the Risk Factors for Chorangiomatosis of Placenta? (Predisposing Factors)

• Currently, no risk factors have been identified for Chorangiomatosis of Placenta
• Research is being performed to identify the relevant risk factors

It is important to note that having a risk factor does not mean that one will get the condition. A risk factor increases one's chances of getting a condition compared to an individual without the risk factors. Some risk factors are more important than others.
Also, not having a risk factor does not mean that an individual will not get the condition. It is always important to discuss the effect of risk factors with your healthcare provider.

What are the Causes of Chorangiomatosis of Placenta? (Etiology)

• The exact cause of Chorangiomatosis of Placenta is currently unknown
• Studies have shown an association between Chorangiomatosis of Placenta and decreased oxygen supply of placental tissue

What are the Signs and Symptoms of Chorangiomatosis of Placenta?

There are no specific signs and symptoms associated with Chorangiomatosis of Placenta.

How is Chorangiomatosis of Placenta Diagnosed?

A diagnosis of Chorangiomatosis of Placenta is made by the microscopic examination of the placenta.

• Cells and tissues are examined by a pathologist under a microscope. Pathological examination is generally considered to be a ‘gold standard’ for a definitive diagnosis
• The pathologist arrives at a diagnosis after analyzing pathology findings along with clinical information of the patient. A pathologist may perform special studies on tissue samples to aid in the final diagnosis (if required)

Many clinical conditions may have similar signs and symptoms. Your healthcare provider may perform additional tests to rule out other clinical conditions to arrive at a definitive diagnosis.

What are the possible Complications of Chorangiomatosis of Placenta?

Complications due to Chorangiomatosis of Placenta could include:

• Pre-eclampsia: A pregnancy complication characterized by high blood pressure and signs of kidney damage in the mother
• Premature delivery
• Congenital malformation of the fetus
• Growth restriction of the fetus
• Placentomegaly: Enlargement of the placenta

How is Chorangiomatosis of Placenta Treated?

• There is no specific treatment for Chorangiomatosis of Placenta
• Treatment is aimed at managing complications associated with the mother and fetus

How can Chorangiomatosis of Placenta be Prevented?

Currently, there are no definitive methods available to prevent Chorangiomatosis of Placenta.

What is the Prognosis of Chorangiomatosis of Placenta? (Outcomes/Resolutions)

• The prognosis of Chorangiomatosis of Placenta depends upon the extent of involvement of the placental tissue
• Diffuse involvement of placental tissue is associated with worse outcomes

Additional and Relevant Useful Information for Chorangiomatosis of Placenta:

Chorangiomatosis of Placenta has an association with multiple gestations.