What are the other Names for this Condition? (Also known as/Synonyms)

• Blue Naevus of Uterine Cervix
• Blue Nevus of Cervix
• Cervical Blue Naevus

What is Blue Nevus of Uterine Cervix? (Definition/Background Information)

• A nevus is a mole on the skin that can occur on any part of the body. A blue nevus is a benign proliferation of melanocytes (cell that make melanin pigment) in the dermis or skin
• Blue Nevus of Uterine Cervix is a benign lesion that is composed of spindle pigmented cells. In most cases, it is an incidental finding following a hysterectomy procedure (surgical removal of the uterus)
• There are no clearly established risk factors for Blue Nevus of Cervix and the cause of tumor formation is also unknown
• Blue nevi are generally asymptomatic in nature and no significant signs and symptoms or complications are present
• Treatment is generally not required for a Blue Nevus of Uterine Cervix. The prognosis is generally excellent with or without treatment, since these moles are generally benign

Who gets Blue Nevus of Uterine Cervix? (Age and Sex Distribution)

• In general, blue nevus is a benign condition that may be present at birth or form at any age in an individual, which is termed congenital or acquired respectively
• The most common location of a blue nevus is the skin, but a blue nevus in the female genital tract is rare. Nevertheless, the mole may form anywhere in the female genital tract, and a majority are seen on the endocervical canal (within the cervix)
• All racial and ethnic groups are at risk for Blue Nevus of Uterine Cervix, but typically blue nevus are more frequent in fair-skinned individuals (Caucasians)

What are the Risk Factors for Blue Nevus of Uterine Cervix? (Predisposing Factors)

No specific risk factors have been identified for Blue Nevus of Uterine Cervix. However, in general, the risk factors identified for blue nevus of skin (the most common location) include:

• Sun exposure
• Generally, lighter-skinned races or individuals (such as Caucasians of America and Europe) are at a higher risk compared to other darker-skinned racial groups (such as Africans and Asians)

It is important to note that having a risk factor does not mean that one will get the condition. A risk factor increases ones chances of getting a condition compared to an individual without the risk factors. Some risk factors are more important than others.

Also, not having a risk factor does not mean that an individual will not get the condition. It is always important to discuss the effect of risk factors with your healthcare provider.

What are the Causes of Blue Nevus of Uterine Cervix? (Etiology)

• The cause of Blue Nevus of Uterine Cervix formation is unknown
• It is believed to be congenital or acquired due to certain unknown factors. The cause may be probably genetic

What are the Signs and Symptoms of Blue Nevus of Uterine Cervix?

Blue Nevus of Uterine Cervix may not present any signs and symptoms in most cases. The general features of the condition include:

• It is a benign tumor of melanocytic cells. The tumor may occur as a single lesion or may be many in numbers
• The moles are flattened lesions with a maximum size of 2-3 mm. The borders of the nevus may not be well-defined
• The benign nevus is usually slow-growing and pigmented. The color may vary from blue to blue black
• In most cases, the blue nevus is present on the endocervical canal. Nevertheless, it may occur anywhere on the genitalia or genital tract
• A majority of the tumors are observed following a hysterectomy, which is generally performed in middle-aged and older women, for a variety of causes

Blue nevus of skin, in general, occurs early in life and grows in size, as the child becomes an adult. As one age, these moles may become smaller and in many cases, they can even disappear.

How is Blue Nevus of Uterine Cervix Diagnosed?

A Blue Nevus of Uterine Cervix is diagnosed through the following tools:

• Complete physical examination with evaluation of medical history
• A colposcopic examination may show a deeply pigmented area on the surface of the uterine cervix
• Tissue biopsy: A tissue biopsy is performed and sent to a laboratory for a pathological examination. The pathologist examines the biopsy under a microscope. After putting together clinical findings, special studies on tissues (if needed) and with microscope findings, the pathologist arrives at a definitive diagnosis
• Blue nevi are normally an incidental finding on examination of the hysterectomy specimen (surgically removed uterus)

Note: In majority of the cases, no biopsy is necessary. But they may be performed to rule out other conditions presenting similar signs and symptoms, such as a melanoma.

Many clinical conditions may have similar signs and symptoms. Your healthcare provider may perform additional tests to rule out other clinical conditions to arrive at a definitive diagnosis.

What are the possible Complications of Blue Nevus of Uterine Cervix?

• There are frequently no complications that arise from a Blue Nevus of Uterine Cervix
• Very rarely, blue nevus may be seen along with malignant melanoma, which may need to be investigated by a healthcare provider
• However, typically a blue nevus does not transform into a melanoma 

How is Blue Nevus of Uterine Cervix Treated?

The treatment measures for Blue Nevus of Uterine Cervix include:

• In many cases, a blue nevus may raise a suspicion for a melanoma. Hence, a tissue biopsy may be performed. Once a diagnosis of Blue Nevus of Uterine Cervix is made, the healthcare provider may chose to regularly observe the benign mole and a “wait and watch” approach may be followed
• Surgical excision and removal of the mole, if necessary, in very rare cases may be undertaken. The type of surgical excision undertaken is dependent upon the size and location of blue nevus on the surface

How can Blue Nevus of Uterine Cervix be Prevented?

Current medical research has not established a method of preventing the occurrence of Blue Nevus of Uterine Cervix.

What is the Prognosis of Blue Nevus of Uterine Cervix? (Outcomes/Resolutions)

The prognosis of Blue Nevus of Uterine Cervix is excellent, since it is a benign tumor.

Additional and Relevant Useful Information for Blue Nevus of Uterine Cervix:

• A blue nevus is a benign proliferation of melanocytes in the dermis/skin

The following link can help you understand blue nevus:

http://www.dovemed.com/diseases-conditions/blue-nevus/