Obesity has been identified as an adverse risk factor for survival in many adult and childhood cancers, but not in pediatric Hodgkin lymphoma, the most common cancer in adolescents. The results of a study led by researchers at Roswell Park Cancer Institute (RPCI) and Columbia University Medical Center used advanced imaging methods to evaluate obesity and suggest a relationship between obesity and disease relapse. The team's findings will be presented at the American Society of Clinical Oncology (ASCO) 52nd Annual Meeting in Chicago.
The researchers analyzed computed tomography (CT) scans for fat components and lean muscle mass in a group of 101 pediatric patients enrolled in the Children's Oncology Group clinical trial AHODOO31, with a goal of assessing the importance of obesity in Hodgkin lymphoma. The CT scans revealed characteristics such as disease staging and response to chemotherapy. Reduced muscle mass was observed among the group of patients who exhibited symptoms of fevers, weight loss and night sweats related to disease-specific cytokines at diagnosis. Increased fat deposits consistent with obesity were found among the patients who experienced relapse of their disease.
"Body mass index is a crude measure of obesity, and the actual measurement may be obscured by disease-related weight loss. Using imaging methods to evaluate body fat may allow for better determination of at-risk patients," says senior author Kara Kelly, MD, Chair of the Department of Pediatric Oncology at Roswell Park. "This study also indicates a need for further study of nutritional interventions to reduce the risk of fat deposits over the course of treatment and their impact on survival among Hodgkin lymphoma pediatric patients."
The above post is reprinted from materials provided by Roswell Park Cancer Institute. Note: Materials may be edited for content and length.
Disclaimer: DoveMed is not responsible for the adapted accuracy of news releases posted to DoveMed by contributing universities and institutions.
and connect with fellow professionals
At DoveMed, our utmost priority is your well-being. We are an online medical resource dedicated to providing you with accurate and up-to-date information on a wide range of medical topics. But we're more than just an information hub - we genuinely care about your health journey. That's why we offer a variety of products tailored for both healthcare consumers and professionals, because we believe in empowering everyone involved in the care process.
Our mission is to create a user-friendly healthcare technology portal that helps you make better decisions about your overall health and well-being. We understand that navigating the complexities of healthcare can be overwhelming, so we strive to be a reliable and compassionate companion on your path to wellness.
As an impartial and trusted online resource, we connect healthcare seekers, physicians, and hospitals in a marketplace that promotes a higher quality, easy-to-use healthcare experience. You can trust that our content is unbiased and impartial, as it is trusted by physicians, researchers, and university professors around the globe. Importantly, we are not influenced or owned by any pharmaceutical, medical, or media companies. At DoveMed, we are a group of passionate individuals who deeply care about improving health and wellness for people everywhere. Your well-being is at the heart of everything we do.
0 Comments
Please log in to post a comment.