The Royal Swedish Academy of Sciences has awarded the 2015 Nobel Prize for Chemistry to Tomas Lindahl, Paul Modrich, and Aziz Sancar. The three scientists are being recognized for their contribution to the understanding of deoxyribonucleic acid (DNA) repair mechanisms and consequently, how a living cell functions. They will each get an equal share of the Nobel Prize.
DNA is damaged on a daily basis owing to external factors like radiation and free radicals, as well as due to its inherent unstable nature. The knowledge gained from the work of the three Nobel laureates has paved the way for understanding repair mechanisms of DNA in normal cells, and by derivation, defects in such repair mechanisms as underlying cause/s of many diseases, such as Alzheimer’s and cancer.
The following is some information about the awardees and their contributions, as well as the importance of their work:
Dr. Tomas Lindahl:
Dr. Paul Modrich:
Dr. Aziz Sancar:
The Nobel Committee lauds the three laureates’ contributions by stating, “…have provided fundamental insights into how cells function, knowledge that can be used, for instance, in the development of new cancer treatments.”
Written by Mangala Sarkar, Ph.D.
Primary Reference
Press Release. (n.d.). Retrieved October 7, 2015, from http://www.nobelprize.org/nobel_prizes/chemistry/laureates/2015/press.html
DoveMed Resources
Alzheimer's Disease (AD). (n.d.). Retrieved October 7, 2015, from http://www.dovemed.com/alzheimers-disease-ad/
Metastatic Cancer to Skin. (n.d.). Retrieved October 7, 2015, from http://www.dovemed.com/diseases-conditions/metastatic-cancer-skin/
Lung Cancer. (n.d.). Retrieved October 7, 2015, from http://www.dovemed.com/lung-cancer/
Breast Cancer. (n.d.). Retrieved October 7, 2015, from http://www.dovemed.com/breast-cancer/
Additional References
Tomas Lindahl - Interview. (n.d.). Retrieved October 7, 2015, from http://www.nobelprize.org/nobel_prizes/chemistry/laureates/2015/lindahl-interview.html
Paul Modrich - Interview. (n.d.). Retrieved October 7, 2015, from http://www.nobelprize.org/nobel_prizes/chemistry/laureates/2015/modrich-interview.html
Aziz Sancar - Interview. (n.d.). Retrieved October 7, 2015, from http://www.nobelprize.org/nobel_prizes/chemistry/laureates/2015/sancar-interview.html
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