Iridocorneal Endothelial Syndrome (Chandler’s Syndrome)

Iridocorneal Endothelial Syndrome (Chandler’s Syndrome)

Article
Eye & Vision
Diseases & Conditions
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Contributed byKrish Tangella MD, MBADec 16, 2021

The topic Iridocorneal Endothelial Syndrome (Chandler’s Syndrome) you are seeking is a synonym, or alternative name, or is closely related to the medical condition Chandler’s Syndrome.

Quick Summary:

  • Chandler’s Syndrome (CS) is a rare disorder of the eye involving corneal edema (fluid buildup in the cornea), iris distortion, and glaucoma (an illness of eye pressure that can cause eye blindness)
  • Chandler’s Syndrome can affect both males and females during middle-age, though research has shown that women tend to be affected more than men. Currently, no known risk factors are known for the condition
  • The cause of Chandler’s Syndrome is currently not fully understood, but a defective endothelium (a tissue type in the eye) plays a part in the development of the condition. Individuals with Chandler’s Syndrome may experience signs and symptoms such as blurred vision, corneal swelling, and iris distortion
  • A healthcare professional can diagnose Chandler’s Syndrome through an eye examination, analysis of past medical history, and specular microscopy. Upon diagnosis, the healthcare professional can design a treatment regimen to address the symptoms. However, there is no cure for Chandler’s Syndrome currently available
  • Suitable and timely treatment can help improve the prognosis for individuals with Chandler’s Syndrome. Complications that may arise from the condition include glaucoma and vision loss. The prognosis can be poor, if early treatment to control the signs and symptoms is not undertaken

Please find comprehensive information on Chandler’s Syndrome regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

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