Cutaneous Lymphomatoid Granulomatosis

Cutaneous Lymphomatoid Granulomatosis

Article
Skin Care
Diseases & Conditions
+1
Contributed byKrish Tangella MD, MBAMar 29, 2018

The topic Cutaneous Lymphomatoid Granulomatosis you are seeking is a synonym, or alternative name, or is closely related to the medical condition Lymphomatoid Granulomatosis of Skin.

Quick Summary:

  • Intravascular Large B-Cell Lymphoma (ILBCL) of Skin is a cutaneous B-cell non-Hodgkin’s lymphoma. It is difficult to find primary cutaneous ILBCL. The condition is usually systemic affecting the lymph nodes, which then affects the skin
  • There are no specific risk factors for the condition and the cause of Intravascular Large B-Cell Lymphoma of Skin is generally unknown. Certain genetic mutations are suspected, which have not been well-characterized
  • Intravascular Large B-Cell Lymphoma of Skin is characterized by the presence of painful skin nodules on the body (mostly on the lower legs), which can result in skin specific signs and symptoms. However, normally the condition is systemic and the signs and symptoms depend upon the body part affected
  • Chemotherapy and/or radiotherapy is generally used to treat Intravascular Large B-Cell Lymphoma of Skin. When the condition affects the skin, the treatment is directed towards controlling the growth and progression of the skin lesions
  • The prognosis depends on many factors including the type of lymphoma, progression of the condition, response to treatment, and overall health of the individual. In general, the prognosis is guarded and is based upon the stage of the tumor

There are different subtypes of Primary Cutaneous Diffuse Large B-Cell Lymphoma. They include:

  • Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type
  • T-Cell/Histiocyte-Rich Large B-Cell Lymphoma of Skin
  • Plasmablastic Lymphoma of Skin
  • Intravascular Large B-Cell Lymphoma of Skin
  • Lymphomatoid Granulomatosis of Skin
  • Cutaneous Diffuse Large B-Cell Lymphoma, Other

General information on lymphoma and lymphocytes:

  • Lymphoma is a type of cancer stemming from uncontrollably dividing lymphocytes (type of white blood cells). There are two types of lymphomas:
    • Hodgkin lymphoma
    • Non-Hodgkin lymphoma
  • Lymphocytes are the main white blood cells found in the lymph, which is the fluid of the lymphatic system; just as blood is the fluid of the circulatory system
  • Lymphocytes are made in bone marrow, and can develop into either B-cells or T-cells. Intravascular Large B-Cell Lymphoma of Skin arises from cancerous B-cells
  • Lymph results from filtration of blood as it travels to and from tissues. Lymph is colorless because it lacks red blood cells; instead, it contains lymphocytes. It is central to the immune system
  • There are 3 different kinds of lymphocytes:
    • T-lymphocytes or T cells: They help combat infections and abnormalities within the cells (cell-mediated immunity). They fight viruses and cancerous cells
    • B-lymphocytes or B cells: They produce antibodies that are bodily defense proteins, which target foreign invaders outside the cells (humoral immunity). They fight bacterial cells, cell fragments, and other immunogenic elements
    • Natural killer cells or NK cells: They perform diverse functions related to both cell-mediated and humoral immunity. They also scout for cancer cells, a process called immune surveillance

Please find comprehensive information on Lymphomatoid Granulomatosis of Skin regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

Was this article helpful

On the Article

Krish Tangella MD, MBA picture
Approved by

Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

0 Comments

Please log in to post a comment.

Related Articles

Test Your Knowledge

Asked by users

Related Centers

Loading

Related Specialties

Loading card

Related Physicians

Related Procedures

Related Resources

Join DoveHubs

and connect with fellow professionals

Related Directories

Who we are

At DoveMed, our utmost priority is your well-being. We are an online medical resource dedicated to providing you with accurate and up-to-date information on a wide range of medical topics. But we're more than just an information hub - we genuinely care about your health journey. That's why we offer a variety of products tailored for both healthcare consumers and professionals, because we believe in empowering everyone involved in the care process.
Our mission is to create a user-friendly healthcare technology portal that helps you make better decisions about your overall health and well-being. We understand that navigating the complexities of healthcare can be overwhelming, so we strive to be a reliable and compassionate companion on your path to wellness.
As an impartial and trusted online resource, we connect healthcare seekers, physicians, and hospitals in a marketplace that promotes a higher quality, easy-to-use healthcare experience. You can trust that our content is unbiased and impartial, as it is trusted by physicians, researchers, and university professors around the globe. Importantly, we are not influenced or owned by any pharmaceutical, medical, or media companies. At DoveMed, we are a group of passionate individuals who deeply care about improving health and wellness for people everywhere. Your well-being is at the heart of everything we do.

© 2023 DoveMed. All rights reserved. It is not the intention of DoveMed to provide specific medical advice. DoveMed urges its users to consult a qualified healthcare professional for diagnosis and answers to their personal medical questions. Always call 911 (or your local emergency number) if you have a medical emergency!