Colonic Lymphoma

Colonic Lymphoma

Article
Digestive Health
Diseases & Conditions
+3
Contributed byMaulik P. Purohit MD MPHNov 06, 2020

The topic Colonic Lymphoma you are seeking is a synonym, or alternative name, or is closely related to the medical condition Lymphoma of Colon and Rectum.

Quick Summary:

  • Lymphoma of Colon and Rectum is an uncommon lymphoma, which is generally observed in elderly men and women. It is also known as Large Bowel Lymphoma or Colorectal Lymphoma
  • The condition may be primary (more common) or secondary:
    • Primary Lymphoma of Colon and Rectum: This type of lymphoma first involves the large intestine and later can involve other parts of the body including the lymph nodes and bone marrow
    • Secondary Lymphoma of Colon and Rectum: This type of lymphoma involves other parts of the body first, such as peripheral blood, lymph nodes, bone marrow, and other organs; colonic and rectal involvement occurs later
  • Lymphoma of Colon and Rectum can either be a B-cell lymphoma or a T-cell lymphoma. B-cell lymphomas are far more common than T-cell lymphomas
  • There are various (histological) subtypes of Colorectal Lymphomas and some of these include:
    • Diffuse large B-cell lymphoma of colon & rectum; the most common type
    • MALT lymphoma of colon & rectum; the second most common type
    • Mantle cell lymphoma of colon & rectum
  • Lymphoma of Colon & Rectum may be associated with autoimmune disorders and inflammatory bowel diseases. It can cause abdominal pain, diarrhea, gastrointestinal tract bleeding, and other general signs and symptoms, such as fever, weight loss, and appetite loss
  • Chemotherapy, surgery, radiation therapy, and other treatment measures may be used for treating Lymphoma of Colon and Rectum based on the assessment of the physician
  • The prognosis depends on many factors including the subtype and stage of lymphoma, progression of the condition, response to treatment, and overall health of the individual. In general, the prognosis of Lymphoma of Colon and Rectum is guarded

General information on lymphoma and lymphocytes:

  • Lymphoma is a type of cancer stemming from uncontrollably dividing lymphocytes (type of white blood cells). There are two types of lymphomas:
    • Hodgkin lymphoma
    • Non-Hodgkin lymphoma
  • Lymphocytes are the main white blood cells found in the lymph, which is the fluid of the lymphatic system; just as blood is the fluid of the circulatory system
  • Lymphocytes are made in bone marrow, and can develop into either B-cells or T-cells. Gastrointestinal Follicular Lymphoma arises from cancerous B-cells
  • Lymph results from filtration of blood as it travels to and from tissues. Lymph is colorless because it lacks red blood cells; instead, it contains lymphocytes. It is central to the immune system
  • There are 3 different kinds of lymphocytes:
    • T-lymphocytes or T cells: They help combat infections and abnormalities within the cells (cell-mediated immunity). They fight viruses and cancerous cells
    • B-lymphocytes or B cells: They produce antibodies that are bodily defense proteins, which target foreign invaders outside the cells (humoral immunity). They fight bacterial cells, cell fragments, and other immunogenic elements
    • Natural killer cells or NK cells: They perform diverse functions related to both cell-mediated and humoral immunity. They also scout for cancer cells, a process called immune surveillance

Please find comprehensive information on Lymphoma of Colon and Rectum regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Maulik P. Purohit MD MPH picture
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Maulik P. Purohit MD MPH

Assistant Medical Director, Medical Editorial Board, DoveMed Team

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