Cerebral Vascular Malformations

Cerebral Vascular Malformations

Article
Brain & Nerve
Heart & Vascular Health
+1
Contributed byKrish Tangella MD, MBAApr 03, 2018

The topic Cerebral Vascular Malformations you are seeking is a synonym, or alternative name, or is closely related to the medical condition Vascular Malformations of the Brain.

Quick Summary:

  • Vascular Malformations of the Brain (VMB) is a collective term designated to describe abnormalities in the formation and structure of the blood vessels, and their subsequent malfunction in the brain
  • It may affect individuals of a wide age range including infants, young children, and adults. The symptoms, in most cases, begin appearing in early adulthood, although these brain malformations can occur at any age
  • Vascular Malformations of the Brain encompasses 6 different conditions, namely:
    • Arteriovenous malformation (AVM): A condition is which abnormal arteries and veins that are enlarged and twisted. This is the most common of the malformations, and is believed to begin forming in early developmental stages, when capillaries that connect arteries and veins are missing in parts of the brain, resulting in abnormal connections. The size of the tangled structures are variable, and can often reach several centimeters in diameter
    • Cavernous malformations (CM); enlarged blood filled spaces are observed in the brain
    • Venous malformations or venous angiomas, in which abnormally-enlarged veins are observed
    • Telangiectasia causing enlarged capillaries
    • Vein of Galen malformation (VGM): The vein of Galen is a large vein that carries deoxygenated blood to the heart from the brain. The supporting fibrous wall to the vein is absent in VGM, making the vein vulnerable to blood pressure changes
    • Mixed malformations (MM): As the name suggests, it is a condition when any combination of the above 5 abnormalities is found together. Most often, arteriovenous malformations and telangiectasia are the conditions that coexist together
  • The risk factors have not been clearly identified for these disorders. However, having a family history of Vascular Malformations of the Brain may pose some risk for developing the condition
  • When a genetic basis is known, the condition is mostly inherited in an autosomal dominant manner. In this type of inheritance, a single copy of the defective gene in each of an individual’s cells, is enough to cause the disorder
  • The signs and symptoms of Vascular Malformations of the Brain may include headaches, numbness, weakness, and seizures. An audible whooshing sound may be heard from the skull with a stethoscope
  • A healthcare professional may perform a physical examination, assess symptoms and evaluate personal and family medical history towards establishing a diagnosis of Vascular Malformations of the Brain. The affected individual is often referred to a specialist, who may conduct imaging studies, such as computed tomography (CT), magnetic resonance imaging (MRI) scans, and cerebral arteriography, to arrive at a final diagnosis
  • Some potential complications from Vascular Malformations of the Brain include bleeding in the brain, stroke, loss of vision, memory problems, difficulties with speech, and severe damage to the brain
  • The treatment for Vascular Malformations of the Brain is determined by the size and location of the malformations. The affected individual may be prescribed medication for headaches and seizures. The abnormality may also be removed surgically, where possible
  • The prognosis of Vascular Malformations of the Brain depends on the severity of the condition. If no complications arise, the outcome is generally positive

Please find comprehensive information on Vascular Malformations of the Brain regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Krish Tangella MD, MBA picture
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Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

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