Central Retinal Vein Occlusion (CRVO)

Central Retinal Vein Occlusion (CRVO)

Article
Eye & Vision
Heart & Vascular Health
+1
Contributed byMaulik P. Purohit MD MPHApr 02, 2018

The topic Central Retinal Vein Occlusion (CRVO) you are seeking is a synonym, or alternative name, or is closely related to the medical condition Retinal Vein Occlusion.

Quick Summary:

  • Retinal Vein Occlusion (RVO) is defined as a blockage in the retinal vein, which drains blood away from the retina. The blockage causes blood to pool into the retinal blood vessels. This causes the walls of the vein to leak blood and excess fluid into the retina, resulting in hemorrhages (or bleeding) and edema (swelling due to leakage of fluid)
  • The retina is a thin layer lining the back of the eye. It is the site where the image gets focused by the eye lens. It is made up of neurons (nerve cells) and connected to the optic nerve. Its main function is to transmit the visual stimulus it receives to the brain
  • The retina is nourished by blood flow from the central retinal artery that supplies oxygen and nutrients that the nerve cells need. Conversely, the central retinal vein, takes away metabolic waste products away from the retina
  • There are two types of RVO, based on where the blockage occurs:
    • Central Retinal Vein Occlusion (CRVO); if the clot occurs in the main retinal vein. CRVO may be of 2 types - ischemic or non-ischemic
    • Branch Retinal Vein Occlusion (BRVO); when the clot occurs in one or more branches of the main retinal vein
  • Retinal Vein Occlusion is most common in individuals with conditions that lead to thickening of blood vessels. The risk factors include health conditions, such as diabetes, atherosclerosis, and high blood pressure, smoking habit, and certain congenital disorders
  • The signs and symptoms of Retinal Vein Occlusion may include dark specks in the field of vision (called eye floaters) and partial or complete blurring of the visual field
  • The condition is diagnosed on the basis of assessment of symptoms and eye examinations that include vision acuity, fluorescein angiography, and testing of the retina and macula
  • There is no effective cure for most cases of Retinal Vein Occlusion. The treatment measures are aimed at delaying progression of the condition and preventing further retinal damage (such as by managing pre-existing medical conditions)
  • The preventive measures for Retinal Vein Occlusion may include maintaining a good glycemic index, routine physical activity, keeping blood pressure under control, and managing one’s body weight
  • The type of Retinal Vein Occlusion and the extent of its progression, prior to medical intervention, may determine the prognosis of the condition. Typically, those with non-ischemic CRVO have a better outcome than individuals with ischemic CRVO

Central Retinal Vein Occlusion is further classified into 2 types, based on whether the occlusion/blockage is complete or partial:

  • Ischemic CRVO: The blood vessels are progressively closed-off, which causes the retinal tissue to be deprived of fresh blood carrying nutrients and oxygen. This in turn, triggers the formation of new blood vessels (capillaries), to seek fresh nutrients and oxygen
  • Non-ischemic CRVO: It is the most common form of CRVO. It is a milder form and no ischemia and neovascularization are observed. Also, no significant complications are noted; however, the non-ischemic type can change to the ischemic type over the course of a few months to years, if left untreated

Please find comprehensive information on Retinal Vein Occlusion regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Maulik P. Purohit MD MPH

Assistant Medical Director, Medical Editorial Board, DoveMed Team

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