Cavernous Angioma of the Brain

Cavernous Angioma of the Brain

Article
Brain & Nerve
Heart & Vascular Health
+2
Contributed byKrish Tangella MD, MBADec 11, 2021

The topic Cavernous Angioma of the Brain you are seeking is a synonym, or alternative name, or is closely related to the medical condition Cavernous Malformations of the Brain.

Quick Summary:

  • Cavernous Malformation of the Brain or CCM is a kind of brain malformation that leads to enlarged blood filled spaces in the brain. The cavernous malformations or cavernomas can exist in any part of the brain, as well as in the spinal cord
  • Most cases are reported in adults, but children may also be affected. Generally, two types of CCM have been identified:
    • Sporadic CCM, which occurs without any family history of the condition
    • Familial CCM, which is the inherited form and it accounts for 20% of the reported cases
  • Having a family history of this disorder is a known risk factor for being diagnosed with the familial form of Cavernous Malformation of the Brain. However, the risk factors for the sporadic form are unknown
  • Genetic mutations in CCM1, CCM2, or CCM3 genes have been linked to Cavernous Malformation of the Brain development. These gene mutations are known to cause multiple cavernomas
  • When a genetic basis is known, the condition is mostly inherited in an autosomal dominant manner. In this type of inheritance, a single copy of the defective gene in each of an individual’s cells, is enough to cause the disorder
  • In the sporadic type of Cavernous Malformation of the Brain, mutations have been reported to occur spontaneously, and the mechanism of disease development is reportedly similar in manner to the inherited form
  • Individuals with CCM can be symptomless, or present symptoms with varying degrees of severity. Some common symptoms include headaches, numbness, weakness in arms and legs, double vision, and speech impediment
  • A healthcare professional may perform a physical examination, assess symptoms and evaluate personal and family medical history towards establishing a diagnosis of Cavernous Malformations of the Brain. The affected individual is often referred to a specialist, who may conduct imaging studies, such as computed axial tomography (CT) and magnetic resonance imaging (MRI) scans to arrive at a final diagnosis
  • Some potential complications from Cavernous Malformations of the Brain include bleeding in the brain, stroke, loss of vision, paralysis, memory problems, difficulties with speech, and damage to the brain
  • The treatment for Cavernous Malformations of the Brain is determined by the size and location of the malformations. The affected individual may be prescribed medication for headaches and seizures. The abnormality may also be removed surgically, where possible
  • The prognosis of Cavernous Malformations of the Brain depends on the severity of the condition. If no complications are noted, then the outcome is generally positive

Please find comprehensive information on Cavernous Malformations of the Brain regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

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