Casals Necklace

Casals Necklace

Article
Brain & Nerve
Digestive Health
+4
Contributed byMaulik P. Purohit MD MPHSep 02, 2020

The topic Casals Necklace you are seeking is a synonym, or alternative name, or is closely related to the medical condition Pellagra.

Quick Summary:

  • Pellagra is a Vitamin B3 Deficiency disorder caused by poor intake of dietary vitamin B3
  • The condition manifests as 4 “Ds”, which indicate dermatitis, diarrhea, dementia, and death. All the 4 manifestations may not occur in an individual; although if the condition is left untreated, it may be fatal
  • This disease used to be prevalent in poor socioeconomic sections of the society, whose staple diet (of corn and maize) was lacking in vitamin B3 (or niacin)
  • Pellagra is classified into two types:
    • Primary Pellagra, which is caused by dietary deficiency of niacin
    • Secondary Pellagra, which is caused by the malabsorption of niacin resulting from some underlying diseases or conditions, the use of certain medications, etc.
  • Vitamin B3 or niacin is used by the body to metabolize food into energy. The vitamin also acts as a scavenger and removes the free oxygen radicals, thus preventing damage to the intracellular proteins
  • Oral supplementation of niacin can reverse the clinical manifestations of the deficiency disorder and correct the condition. This is also indicative of Pellagra

Please find comprehensive information on Pellagra regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Maulik P. Purohit MD MPH

Assistant Medical Director, Medical Editorial Board, DoveMed Team

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