Cardiac Lymphoma

Cardiac Lymphoma

Article
Heart & Vascular Health
Diseases & Conditions
+1
Contributed byKrish Tangella MD, MBAAug 29, 2023

The topic Cardiac Lymphoma you are seeking is a synonym, or alternative name, or is closely related to the medical condition Lymphoma of Heart.

Quick Summary:

  • Lymphoma of Heart (or Cardiac Lymphoma) is a rare, B-cell non-Hodgkin’s lymphoma. Even though the heart is almost always involved, its involvement is often secondary to systemic malignancy. This means that the lymphoma may have originated in other part of the body
  • Cardiac Lymphoma is generally aggressive and nearly 80% of the tumor type is diffuse large B-cell type lymphoma (DLBCL). In rare cases, some types are Burkitt lymphomas
  • Primary Lymphoma of Heart is rare, with only a few cases being reported. Majority of the bulk of the tumor is confined to the heart. In order for the tumor to be called a primary Lymphoma of Heart, the tumor should originate in the heart. Given the rarity of the tumor, the diagnosis of Lymphoma of Heart is often difficult to make
  • There are no specific risk factors for the condition and the cause of Lymphoma of Heart is generally unknown. Certain genetic mutations are suspected, which have not been well-characterized
  • Lymphoma of Heart primarily affects the heart leading to chest pain, dizziness, and acute heart failure. There may be other presentations depending on the different body part affected. The general signs and symptoms may include weight loss, fatigue, headaches, and frequent infections
  • Chemotherapy and radiotherapy is generally used to treat Lymphoma of Heart. The treatment is also directed towards addressing specific signs and symptoms based on the organs involved
  • The prognosis depends on many factors including the type of lymphoma, progression of the condition, response to treatment, and overall health of the individual. In general, the prognosis of Lymphoma of Heart is often poor

General information on lymphoma and lymphocytes:

  • Lymphoma is a type of cancer stemming from uncontrollably dividing lymphocytes (type of white blood cells). There are two types of lymphomas:
    • Hodgkin lymphoma
    • Non-Hodgkin lymphoma
  • Lymphocytes are the main white blood cells found in the lymph, which is the fluid of the lymphatic system; just as blood is the fluid of the circulatory system
  • Lymphocytes are made in bone marrow, and can develop into either B-cells or T-cells. Lymphoma of Heart arises from cancerous B-cells
  • Lymph results from filtration of blood as it travels to and from tissues. Lymph is colorless because it lacks red blood cells; instead, it contains lymphocytes. It is central to the immune system
  • There are 3 different kinds of lymphocytes:
    • T-lymphocytes or T cells: They help combat infections and abnormalities within the cells (cell-mediated immunity). They fight viruses and cancerous cells
    • B-lymphocytes or B cells: They produce antibodies that are bodily defense proteins, which target foreign invaders outside the cells (humoral immunity). They fight bacterial cells, cell fragments, and other immunogenic elements
    • Natural killer cells or NK cells: They perform diverse functions related to both cell-mediated and humoral immunity. They also scout for cancer cells, a process called immune surveillance

Please find comprehensive information on Lymphoma of Heart regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Krish Tangella MD, MBA picture
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Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

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