The topic Burkitt's Tumor of Uterus you are seeking is a synonym, or alternative name, or is closely related to the medical condition Primary Burkitt Lymphoma of Uterus.
Quick Summary:
- Burkitt lymphoma is a very aggressive and fast-growing form of non-Hodgkin lymphoma. The lymphoma affects the B-cells of the immune system. Burkitt Lymphoma of Uterus is an uncommon condition that is seen in adult women
- Primary Burkitt Lymphoma of Uterus is a rare subtype of lymphoma that first involves the uterus. In general, the lymphoma involves other parts of the body first, such as peripheral blood, lymph nodes, bone marrow, and other organs; involvement of the uterus is noted much later (termed secondary type of Follicular Lymphoma of Uterus)
- Burkitt’s lymphoma, in general, may be of the following types:
- Endemic Burkitt Lymphoma: This type of lymphoma is common wherever Burkitt lymphoma is endemic in Africa. It is generally associated with Epstein-Barr virus (EBV)
- Sporadic Burkitt Lymphoma: This type is similar to the endemic form of Burkitt lymphoma, but occurs in other parts of the world (outside Africa). It is more infrequent and is generally not associated with EBV infection
- A majority of cases of Primary Burkitt Lymphoma of Uterus are of the sporadic type. The specific cause of the lymphoma is currently unknown. Nevertheless, certain genetic defects have been implicated, particularly in the c-MYC gene. No specific risk factors for this lymphoma type have been identified
- Primary Burkitt Lymphoma of Uterus can cause abnormal vaginal bleeding; in some cases, pelvic pain and other general signs and symptoms, such as anemia, fatigue, and appetite loss, are noted. A diagnosis is typically made with the biopsy of the affected lymph node or tumor tissue
- Burkitt lymphoma is generally treated with chemotherapy supplemented with monoclonal antibody treatment. The standard of care is intensive chemotherapy; but, a new clinical study has determined that low-intensity chemotherapy may be effective in some cases. This provides the added benefit of less toxicity
- Primary Burkitt Lymphoma of Uterus is a high-grade malignancy. The prognosis of the condition is dependent upon a set of factors, most importantly the stage of the cancer. The prognosis is generally guarded
General information on lymphoma and lymphocytes:
- Lymphoma is a type of cancer stemming from uncontrollably dividing lymphocytes (type of white blood cells). There are two types of lymphomas:
- Hodgkin lymphoma
- Non-Hodgkin lymphoma
- Lymphocytes are the main white blood cells found in the lymph, which is the fluid of the lymphatic system; just as blood is the fluid of the circulatory system
- Lymphocytes are made in bone marrow, and can develop into either B-cells or T-cells. Burkitt Lymphoma of Uterus arises from cancerous B-cells
- Lymph results from filtration of blood as it travels to and from tissues. Lymph is colorless because it lacks red blood cells; instead, it contains lymphocytes. It is central to the immune system
- There are 3 different kinds of lymphocytes:
- T-lymphocytes or T cells: They help combat infections and abnormalities within the cells (cell-mediated immunity). They fight viruses and cancerous cells
- B-lymphocytes or B cells: They produce antibodies that are bodily defense proteins, which target foreign invaders outside the cells (humoral immunity). They fight bacterial cells, cell fragments, and other immunogenic elements
- Natural killer cells or NK cells: They perform diverse functions related to both cell-mediated and humoral immunity. They also scout for cancer cells, a process called immune surveillance
Please find comprehensive information on Primary Burkitt Lymphoma of Uterus regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.
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