Brain Actinomycosis

Brain Actinomycosis

Article
Brain & Nerve
Infectious Diseases
Contributed byKrish Tangella MD, MBAMar 11, 2018

The topic Brain Actinomycosis you are seeking is a synonym, or alternative name, or is closely related to the medical condition Central Nervous System Actinomycosis.

Quick Summary:

  • Central Nervous System (CNS) Actinomycosis is a rare and chronic infection, caused predominantly by the bacterium Actinomyces israelii, and to a lesser extent by other Actinomyces species
  • They exist naturally in the mucous lining of the nose, throat, mouth, digestive tract, and female reproductive tract, and are not normally harmful. These anaerobic bacteria have the ability to grow in the absence of oxygen, or in reduced concentrations of oxygen
  • However, any injury, trauma or surgical procedure can cause the bacterial cells to gain entry into deep tissues where they are not normally present. Since these bacteria can grow without oxygen, they can thrive in such environments, resulting in infection
  • Central Nervous System Actinomycosis may result from infection, following a head injury or through spread of actinomycosis from other parts of the body, either through direct contact or blood
  • The bacteria are slow-growing and the infection leads to the formation of hard, red or purple pus-filled abscess in the affected tissue. The abscess may drain and this can be accompanied by pain and fever. The condition can occur in all age groups and may be manifested as localized sensory loss, numbness, and seizures
  • Examination of the fluid drainage under microscope and culture of affected tissue specimen and imaging techniques may be employed to diagnose CNS Actinomycosis. The pus or drainage is checked for “sulfur granules”
  • Prolonged treatment with antibiotics is necessary to remove the infection. In some cases, the abscess may need to be surgically drained or removed
  • With prompt diagnosis and sustained treatment, Central Nervous System Actinomycosis is curable. However, if the infection becomes generalized via spread of bacteria through the bloodstream, it can spread to other organs and tissues. In such cases, the recovery can be prolonged

Please find comprehensive information on Central Nervous System Actinomycosis regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

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