Angioendotheliotropic Lymphoma of Lung

Angioendotheliotropic Lymphoma of Lung

Article
Healthy Lungs
Diseases & Conditions
+2
Contributed byKrish Tangella MD, MBAFeb 02, 2024

The topic Angioendotheliotropic Lymphoma of Lung you are seeking is a synonym, or alternative name, or is closely related to the medical condition Intravascular Large B-Cell Lymphoma of Lung.

Quick Summary:

  • Intravascular Large B-Cell Lymphoma (ILBCL) of Lung is a very uncommon, B-cell non-Hodgkin’s lymphoma. The condition is usually systemic and can affect the central nervous system; however, for some reason the lymph nodes are spared
  • There are no specific risk factors for the condition and the cause of Intravascular Large B-Cell Lymphoma of Lung is generally unknown. Certain genetic mutations are suspected, which have not been well-characterized
  • Intravascular Large B-Cell Lymphoma of Lung manifestations may include pulmonary embolism, low oxygen levels in blood, and widespread lung disease. The general signs and symptoms may include weight loss, fatigue, headaches, and frequent infections. However, due to the set of non-specific symptoms observed, the diagnosis of ILBCL is often delayed
  • Chemotherapy and radiotherapy is generally used to treat Pulmonary Intravascular Large B-Cell Lymphoma. The treatment is directed towards addressing specific signs and symptoms based on the organs involved
  • The prognosis depends on many factors including the type of lymphoma, progression of the condition, response to treatment, and overall health of the individual. In general, the prognosis of Intravascular Large B-Cell Lymphoma of Lung is often poor

General information on lymphoma and lymphocytes:

  • Lymphoma is a type of cancer stemming from uncontrollably dividing lymphocytes (type of white blood cells). There are two types of lymphomas:
    • Hodgkin lymphoma
    • Non-Hodgkin lymphoma
  • Lymphocytes are the main white blood cells found in the lymph, which is the fluid of the lymphatic system; just as blood is the fluid of the circulatory system
  • Lymphocytes are made in bone marrow, and can develop into either B-cells or T-cells. Intravascular Large B-Cell Lymphoma arises from cancerous B-cells
  • Lymph results from filtration of blood as it travels to and from tissues. Lymph is colorless because it lacks red blood cells; instead, it contains lymphocytes. It is central to the immune system
  • There are 3 different kinds of lymphocytes:
    • T-lymphocytes or T cells: They help combat infections and abnormalities within the cells (cell-mediated immunity). They fight viruses and cancerous cells
    • B-lymphocytes or B cells: They produce antibodies that are bodily defense proteins, which target foreign invaders outside the cells (humoral immunity). They fight bacterial cells, cell fragments, and other immunogenic elements
    • Natural killer cells or NK cells: They perform diverse functions related to both cell-mediated and humoral immunity. They also scout for cancer cells, a process called immune surveillance

Please find comprehensive information on Intravascular Large B-Cell Lymphoma of Lung regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Krish Tangella MD, MBA picture
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Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

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