Angiocentric T-Cell Lymphoma (Extranodal NK/T Cell Lymphoma, Nasal type)

Angiocentric T-Cell Lymphoma (Extranodal NK/T Cell Lymphoma, Nasal type)

Article
Ear, Nose, & Throat (ENT)
Diseases & Conditions
+3
Contributed byKrish Tangella MD, MBAFeb 17, 2022

The topic Angiocentric T-Cell Lymphoma (Extranodal NK/T Cell Lymphoma, Nasal type) you are seeking is a synonym, or alternative name, or is closely related to the medical condition Extranodal NK/T-Cell Lymphoma, Nasal type.

Quick Summary:

  • Extranodal NK/T Cell Lymphoma, Nasal type (ENKL) is a rare type of ‘extranodal lymphoma’ that usually develops in the nose, nasal passage, and paranasal sinuses. This is the reason why it is named “nasal type,” though it may arise at other locations too
  • Extranodal lymphomas develop outside of the lymph nodes and can be found in body tissues, like the skin, tonsils, brain, bowels, and bone
  • Lymphoma is a type of blood cancer stemming from uncontrollably dividing lymphocytes (type of white blood cells). There are two types of lymphomas:
    • Hodgkin Lymphoma
    • Non-Hodgkin Lymphoma
  • NK/T Cell Lymphoma is a type of non-Hodgkin lymphoma. They are differentiated by detecting the type of proteins expressed on the surface of the cancer cells, and by the way they look under a microscope, when examined by a pathologist
  • Lymphocytes are a class of white blood cells that are part of the lymphatic system. Lymphocytes are made in bone marrow, and can develop into either B-cells or T-cells. There is also another class of lymphocytes called natural killer cells (NK cells); NK/T cells are a type of T cells. An NK/T Cell Lymphoma arises from cancerous T-cells
  • Normally, lymphocytes help generate an immune response to infections. These cells can recognize a wide variety of foreign invaders. They can also remember them and respond accordingly, if the body is infected with the same bacteria/virus ever again
  • The lymphatic system is responsible for immunity to diseases. The organs of the lymphatic system are lymph nodes, bone marrow, the spleen, thymus, and tonsils. In children, the T cells are produced in the thymus. As an individual gets older, other parts of the lymphatic system are involved. At that point, they reside in the bone marrow and the thymus shrinks down, becoming inactive
  • T-cells are responsible for recognizing cells that are altered or infected, and it includes attempting to kill cells that are cancerous too
  • Common signs and symptoms of NK/T Cell Lymphoma, Nasal type are nasal bleeding and discharge, nasal blockage, weight loss, and excessive night sweats
  • The condition is generally treated with a combination of radiation therapy and chemotherapy. However, the prognosis for Extranodal NK/T Cell Lymphoma, Nasal type is very poor, with a high risk of relapse (return of the condition after initial treatment)

Please find comprehensive information on Extranodal NK/T-Cell Lymphoma, Nasal type regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Krish Tangella MD, MBA picture
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Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

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