The topic Angiocentric Cutaneous T-Cell Lymphoma of Childhood you are seeking is a synonym, or alternative name, or is closely related to the medical condition Hydroa Vacciniforme-like Cutaneous T-Cell Lymphoma.

Quick Summary:

• Hydroa Vacciniforme-like Cutaneous T-Cell Lymphoma is a rare T-cell non-Hodgkin’s lymphoma that is observed in children. The skin lesions (papules and vesicles) are observed on the sun-exposed areas
• This is a type of primary cutaneous non-Hodgkin lymphoma, which means that it is a lymphoma that originates first in the skin. It can later involve other parts of the body including the lymph nodes and bone marrow; in which case it is called systemic Hydroa Vacciniforme-like Cutaneous T-Cell Lymphoma
• The cause of the condition is not well-established, though certain genetic mutations are suspected. However, Hydroa Vacciniforme-like Cutaneous T-Cell Lymphoma is known to be associated with chronic exposure to sun and Epstein-Barr viral infections
• A treatment may be undertaken depending upon the signs and symptoms observed and this could be skin-directed treatment and/or systemic treatment, when the whole body is affected
• In some children, the condition progresses rapidly, while in others the progress is slower. Nevertheless, in general, the prognosis of Hydroa Vacciniforme-like Cutaneous T-Cell Lymphoma is poor even with treatment

General information on lymphoma and lymphocytes:

• Lymphoma is a type of cancer stemming from uncontrollably dividing lymphocytes (type of white blood cells). There are two types of lymphomas:
  • Hodgkin lymphoma
  • Non-Hodgkin lymphoma
• Lymphocytes are the main white blood cells found in the lymph, which is the fluid of the lymphatic system; just as blood is the fluid of the circulatory system
• Lymphocytes are made in bone marrow, and can develop into either B-cells or T-cells. T-cells mature in the thymus; Hydroa Vacciniforme-like Cutaneous T-Cell Lymphoma arises from cancerous T-cells
• Lymph results from filtration of blood as it travels to and from tissues. Lymph is colorless because it lacks red blood cells; instead, it contains lymphocytes. It is central to the immune system
• There are 3 different kinds of lymphocytes:
  • T-lymphocytes or T cells: They help combat infections and abnormalities within the cells (cell-mediated immunity). They fight viruses and cancerous cells
  • B-lymphocytes or B cells: They produce antibodies that are bodily defense proteins, which target foreign invaders outside the cells (humoral immunity). They fight bacterial cells, cell fragments, and other immunogenic elements
  • Natural killer cells or NK cells: They perform diverse functions related to both cell-mediated and humoral immunity. They also scout for cancer cells, a process called immune surveillance

Please find comprehensive information on Hydroa Vacciniforme-like Cutaneous T-Cell Lymphoma regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.