Andersen Glycogenosis

Andersen Glycogenosis

Article
Digestive Health
Diseases & Conditions
+2
Contributed byKrish Tangella MD, MBAMay 24, 2021

The topic Andersen Glycogenosis you are seeking is a synonym, or alternative name, or is closely related to the medical condition Andersen's Disease.

Quick Summary:

  • Andersen's Disease is rare, inherited disorder that affects the body's metabolic process of synthesis of an important storage substance, called glycogen, in the body. The condition is also known as Glycogen Storage Disease Type IV (or GSD Type IV)
  • Individuals with a family history of the disorder are at risk for developing GSD Type IV. The condition is caused by mutations in the GBE1 gene and inherited in an autosomal recessive manner
  • In Andersen's Disease, there is an abnormal storage of glycogen that takes place in the body. This abnormally-stored glycogen cannot be utilized by the body, resulting in the characteristic signs and symptoms of the condition.
  • These signs and symptoms include reduced blood glucose, decreased muscle mass, weakness, enlarged liver and spleen, and even heart abnormalities. Andersen’s Disease can affect multiple organs and body systems
  • Treatment options for Andersen’s Disease are geared toward addressing the symptoms of the disorder and offering supportive care. For individuals with liver failure, liver transplantation may be recommended
  • Since Andersen’s Disease is an inherited disorder, there are no effective ways of preventing its occurrence. However, genetic counseling of prospective parents with a family history of the disorder may help in a better understanding of the disorder and the likelihood of their offspring developing the same
  • The prognosis of Andersen’s Disease depends on the severity of the condition. Children with milder forms of the disorder have a better prognosis than those with severe signs and symptoms 

Please find comprehensive information on Andersen's Disease regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

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