Amazonic Pseudolephromatous Blastomycosis

Amazonic Pseudolephromatous Blastomycosis

Article
Skin Care
Diseases & Conditions
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Contributed byKrish Tangella MD, MBAFeb 12, 2024

The topic Amazonic Pseudolephromatous Blastomycosis you are seeking is a synonym, or alternative name, or is closely related to the medical condition Lobomycosis.

Quick Summary:

  • Lobomycosis is a skin infection caused by the fungus Lacazia loboi. This fungus is found almost exclusively in South America and some Central American regions
  • Lacazia loboi is generally found in dense forest areas with large water bodies/rivers and high humidity levels (relative humidity at about 75%). The pathogen is naturally found only in dolphins and humans, giving rise to an unsubstantiated speculation that the infection spreads from dolphins to humans
  • Although the human disease is predominantly reported in South and Central America, the infection in dolphins is spreading and has been reported in the coasts of south Brazil, Indian Ocean, Western Pacific, Africa, Europe, and North Carolina (in the USA)
  • Individuals who work with dolphins, forest workers, those who live in the forests of South and Central America, and scientists doing fieldwork in such forests, are at an increased risk of contracting Lobomycosis
  • The fungus establishes itself when there is a break in the skin due to an injury, such as through cuts, scratches, insect or animal bites. After this event occurs, it can take a long time (up to 2 years) before the signs and symptoms of Lobomycosis are manifested in the individual
  • The symptoms of the infection appear predominantly on exposed skin, such as on the ears, arms, and legs. Other body surfaces, such as the chest and face, may also be affected. Superficial or deep nodules and plaques (raised, smooth-surfaced, and hard lesions) may appear on the skin; these may be unpigmented or have different shades of pigmentation
  • Lobomycosis can lead to complications, such as ulceration of the skin lesions and the development of recurrent lesions. In rare cases, the infection may result in squamous cell carcinomas
  • Lobomycosis is diagnosed based on the presenting symptoms, travel or work history of the affected individual to the endemic regions, and microscopic examination of a lesion sample using specific stains, which is performed in a laboratory
  • Removal of lesions and surrounding skin by surgery is considered the most effective method of treating this infection. The use of anti-fungal agents for treatment of Lobomycosis has not yielded satisfactory results
  • The prognosis of Lobomycosis depends on the severity of the signs and symptoms, and response to surgery. Although there is a likelihood of a chronic infection, Lobomycosis is limited to the skin in most cases

Please find comprehensive information on Lobomycosis regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team

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