The topic Acral Mycoses Fungoides you are seeking is a synonym, or alternative name, or is closely related to the medical condition Pagetoid Reticulosis.

Quick Summary:

• Pagetoid Reticulosis is a variant of Mycosis Fungoides, which is a cutaneous T-cell non-Hodgkin’s lymphoma. It is usually present as a single, slow-growing patch or plaque on the arm or leg
• Pagetoid Reticulosis is a rare form of primary cutaneous non-Hodgkin lymphoma, which means that it is a lymphoma that originates in the skin. In rare cases, Pagetoid Reticulosis may later involve additional parts of the body including the lymph nodes and bone marrow. This is known as systemic Pagetoid Reticulosis
• The condition can lead to the formation of skin lesions (papules and plaques) that may ulcerate and cause secondary infections. Widespread symptoms, such as weight loss, fatigue, anemia, fever, and night sweats, can also be present when other body regions are affected
• Pagetoid Reticulosis is typically diagnosed with a biopsy of the affected skin or with a biopsy of the swollen lymph nodes or affected organ. Other diagnostic methods may be used to examine the extent of the condition and its severity
• The treatment is dependent upon the stage of Pagetoid Reticulosis. It may be skin-directed treatment (such as the use of topical medications, phototherapy, or local radiation therapy), or in rare instances, systemic therapy (through a combination of chemotherapy, radiation therapy, and surgery) when other organs are involved
• The prognosis is dependent on many factors including the progression of the condition, response to treatment, and health status of the individual. Generally, the prognosis is good with appropriate, early treatment

General information on lymphoma and lymphocytes:

• Lymphoma is a type of cancer stemming from uncontrollable division of lymphocytes (type of white blood cells). There are two types of lymphomas:
  • Hodgkin lymphoma
  • Non-Hodgkin lymphoma
• Lymphocytes are the primary white blood cells located in the lymph, which is the fluid of the lymphatic system; just as blood is the fluid of the circulatory system
• Lymphocytes are produced in bone marrow, and can mature into either B-cells or T-cells. T-cells mature in the thymus; Pagetoid Reticulosis arises from cancerous T-cells
• Lymph results from filtration of blood as it moves to and from tissues. Lymph is colorless because it contains no red blood cells; instead, it contains lymphocytes. It is central to the immune system
• There are 3 different kinds of lymphocytes:
  • T-lymphocytes or T cells: They help fight infections and irregularities within the cells (cell-mediated immunity). They fight viruses and cancerous cells
  • B-lymphocytes or B cells: They generate antibodies that are bodily defense proteins, which target foreign invaders outside the cells (humoral immunity). They combat bacterial cells, cell fragments, and other immunogenic elements
  • Natural killer cells or NK cells: They perform various functions related to both cell-mediated and humoral immunity. They also search for cancer cells, a process called immune surveillance

Please find comprehensive information on Pagetoid Reticulosis regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.