Acanthosis Nigricans Maligna (ANM)

Acanthosis Nigricans Maligna (ANM)

Article
Skin Care
Diseases & Conditions
+1
Contributed byLester Fahrner, MD+1 moreJun 07, 2022

The topic Acanthosis Nigricans Maligna (ANM) you are seeking is a synonym, or alternative name, or is closely related to the medical condition Malignancy-Associated Acanthosis Nigricans.

Quick Summary:

  • Acanthosis Nigricans (AN) is a skin condition that causes thick, velvety, and darkened skin areas (due to increased thickness of epidermis). It commonly affects the skin of the armpits, the groin region, head and neck (back of the neck), and anal/genital region.
  • Acanthosis Nigricans is not contagious and it cannot be transmitted from one individual to another. It is associated with many disorders, such as obesity, diabetes, and malignancy
  • Malignancy-Associated Acanthosis Nigricans is one among the 7 types of type Acanthosis Nigricans. Acanthosis Nigricans associated with malignancy (or cancer) shares similar features to other types of Acanthosis Nigricans but has a rapid onset. Hence, this type of Acanthosis Nigricans is not a disease by itself, but rather a sign of cancer (known as a paraneoplastic syndrome)
  • Stomach cancer is the most common type of cancer causing Malignancy-Associated Acanthosis Nigricans. It is usually diagnosed by a thorough clinical history and physical examination
  • Even though the skin condition is benign, a dermatologist consultation and testing is necessary to rule out other causes of Acanthosis Nigricans. If malignancy is suspected as an underlying cause, then appropriate workup including imaging studies and blood tests are necessary
  • The treatment of cancer is more important than treatment of the skin lesions caused by Acanthosis Nigricans. The skin lesions may regress with treatment of cancer
  • The prognosis of Malignancy Associated Acanthosis Nigricans depends on several factors, but most importantly on the type of cancer, the stage of cancer, and treatment response of the individual

Please find comprehensive information on Malignancy-Associated Acanthosis Nigricans regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE.

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On the Article

Krish Tangella MD, MBA picture
Approved by

Krish Tangella MD, MBA

Pathology, Medical Editorial Board, DoveMed Team
Lester Fahrner, MD picture
Reviewed by

Lester Fahrner, MD

Chief Medical Officer, DoveMed Team

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